Results 71 to 80 of about 2,148,018 (281)

Fixed and random effects in Classical and Bayesian regression [PDF]

open access: yes
This paper proposes a common and tractable framework for analyzing different definitions of fixed and random effects in a contant-slope variable-intercept model. It is shown that, regardless of whether effects (i) are treated as parameters or as an error
Silvio Rendón
core   +3 more sources

Uso de modelos de regressão aleatória para descrever a variação genética da produção de leite na raça Holandesa Random regressions models to describe the genetic variation of milk yield in Holstein breed

open access: yesRevista Brasileira de Zootecnia, 2006
Registros de produção de leite de 68.523 controles leiteiros de 8.536 vacas da raça Holandesa, com parições nos anos de 1996 a 2001, foram utilizados na comparação entre modelos de regressão aleatória para estimação de componentes de variância.
Cláudio Vieira de Araújo   +8 more
doaj   +1 more source

Kernel Inverse Regression for spatial random fields [PDF]

open access: yes, 2008
In this paper, we propose a dimension reduction model for spatially dependent variables. Namely, we investigate an extension of the \emph{inverse regression} method under strong mixing condition.
Loubes, Jean-Michel   +1 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Impact of simplified methods of growth recording on genetic parameter estimates of Tunisian local goat population under a low input production system

open access: yesItalian Journal of Animal Science, 2020
The study aims to simulate the alternative methods of simplifying weight recording of Tunisian local kids and assesses the impact of their use from a genetic point of view to set up the basis for the future improvement of this important component of ...
A. Atoui   +3 more
doaj   +1 more source

Invariances of random fields paths, with applications in Gaussian Process Regression [PDF]

open access: yes, 2013
We study pathwise invariances of centred random fields that can be controlled through the covariance. A result involving composition operators is obtained in second-order settings, and we show that various path properties including additivity boil down ...
Durrande, Nicolas   +2 more
core   +2 more sources

Conditional density estimation in a regression setting

open access: yes, 2008
Regression problems are traditionally analyzed via univariate characteristics like the regression function, scale function and marginal density of regression errors.
Efromovich, Sam
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Use of gene expression data for predicting continuous phenotypes for animal production and breeding

open access: yesAnimal, 2008
Traits such as disease resistance are costly to evaluate and slow to improve using current methods. Analysis of gene expression profiles (e.g. DNA microarrays) has potential for predicting such phenotypes and has been used in an analogous way to classify
N. Robinson, M. Goddard, B. Hayes
doaj   +1 more source

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