Results 121 to 130 of about 2,891,219 (304)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Independent Random Matching [PDF]

open access: yes
Random matching models with a continuum population are widely used in economics to study environments where agents interact in small coalitions. This paper provides foundations to such models.
Puzzello, Daniela, Podczeck, Konrad
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Computably enumerable sets below random sets

open access: yesAnnals of Pure and Applied Logic, 2012
Intuitively, randomness of a set means, in particular, that there is no algorithmic way to generate this set, while computable enumerability (c.e.) means that the set is generated by an algorithm. Since these two notions are opposite, it may seem reasonable to expect that the only c.e.~sets Turing below a random set are computable ones.
openaire   +1 more source

Depth functions based on a number of observations of a random vector [PDF]

open access: yes
We present two statistical depth functions given in terms of the random variable defined as the minimum number of observations of a random vector that are needed to include a fixed given point in their convex hull.
Ignacio Cascos
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Random measurable sets [PDF]

open access: yes, 2019
The aim of this thesis is to compare two major models of random sets, the well established random closed sets (RACS) and the more recent and more general random measurable sets (RAMS).
Fojtík, Vít
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Existence of solution sets for Φ-Laplacian for random impulsive differential equations

open access: yesAlexandria Engineering Journal
In this article, we provide results on the existence and compactness of the set of solutions for a class of initial-value problem representing a first-order random impulsive differential equation.
Mohamed Ferhat   +5 more
doaj   +1 more source

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