Results 111 to 120 of about 2,891,219 (304)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Layer-2 transferable belief model: Manage uncertainty on random permutation sets
Journal of Electronic Science and TechnologyIn this paper, the transferable belief model established on power sets is extended to the permutation event space (PES) and is referred to as the layer-2 transferable belief model. Our goal is to provide a comprehensive approach for handling and modeling
Qian-Li Zhou, Yong Deng
doaj +1 more source
SOME PRELIMINARY EVIDENCE ON SAMPLING OF ALTERNATIVES WITH THE RANDOM PARAMETERS LOGIT [PDF]
Random utility models rely on the properties of the logistic distribution for ease of estimation, but this distribution implies the independence of irrelevant alternatives (IIA).
McConnell, Kenneth E., Tseng, Wei-Chun
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Random weighted Sidon sets [PDF]
, 2000 We investigate random Sidon-type sets in which the degrees of the representations are weighted. These variants of Sidon sets are of interest as there are compact non-abelian groups which admit no infinite Sidon sets. In this note we determine the largest
Hare, Kathryn
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Random structures for partially ordered sets [PDF]
, 2006 This thesis is presented in two parts. In the first part, we study a family of models of random partial orders, called classical sequential growth models, introduced by Rideout and Sorkin as possible models of discrete space-time.
Georgiou, Nicholas
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
ON THE FRONTIER OF GENERATING REVEALED PREFERENCE CHOICE SETS: AN EFFICIENT APPROACH [PDF]
Deterministic rules for generating choice sets are often employed by analysts confronting universal sets with large numbers of alternatives. For destination choice analysis, site exclusion rules defined by travel time, distance, or quality have a ...
Scrogin, David +3 more
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