Results 91 to 100 of about 2,891,219 (304)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Propagation Models and Fitting Them for the Boolean Random Sets [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2010
In order to study the relationship between random Boolean sets and some explanatory variables, this paper introduces a Propagation model. This model can be applied when corresponding Poisson process of the Boolean model is related to explanatory ...
mojtaba Khazaei, Khalil Shafie
doaj  

NUMERICAL EXPERIMENTS FOR THE ESTIMATION OF MEAN DENSITIES OF RANDOM SETS

open access: yesImage Analysis and Stereology, 2014
Many real phenomena may be modelled as random closed sets in ℝd, of different Hausdorff dimensions. The problem of the estimation of pointwise mean densities of absolutely continuous, and spatially inhomogeneous, random sets with Hausdorff dimension n ...
Federico Camerlenghi   +2 more
doaj   +1 more source

Zero forcing with random sets

open access: yesDiscrete Mathematics
22 pages, 5 ...
Bryan Curtis   +4 more
openaire   +4 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Multifractal Structure of Irregular Sets via Weighted Random Sequences

open access: yesFractal and Fractional
We study the multifractal structure of irregular sets arising from Fibonacci-weighted sums of sequences of random variables. Focusing on Cantor-type subsets Kε of the unit interval, we construct sequences of free and forced blocks, where the free blocks ...
Najmeddine Attia, Taoufik Moulahi
doaj   +1 more source

The Hausdorff dimension and exact Hausdorff measure of random recursive sets with overlapping

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
We weaken the open set condition and define a finite intersection property in the construction of the random recursive sets. We prove that this larger class of random sets are fractals in the sense of Taylor, and give conditions when these sets have ...
Hongwen Guo, Dihe Hu
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Lift expectations of random sets [PDF]

open access: yes, 2019
International audienceIt is known that the distribution of an integrable random vector ξ in Rd isuniquely determined by a (d + 1)-dimensional convex body called the lift zonoidof ξ.
Diaye, Marc-Arthur   +2 more
core   +1 more source

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