Universality for Random Surfaces in Unconstrained Genus [PDF]
Starting from an arbitrary sequence of polygons whose total perimeter is $2n$, we can build an (oriented) surface by pairing their sides in a uniform fashion. Chmutov & Pittel have shown that, regardless of the configuration of polygons we started with, the degree sequence of the graph obtained this way is remarkably constant in total variation ...
Budzinski, Thomas +2 more
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Markov Random Field Surface Reconstruction [PDF]
A method for implicit surface reconstruction is proposed. The novelty in this paper is the adaptation of Markov Random Field regularization of a distance field. The Markov Random Field formulation allows us to integrate both knowledge about the type of surface we wish to reconstruct (the prior) and knowledge about data (the observation model) in an ...
Rasmus R. Paulsen +2 more
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Effect of the Dynamic Load on Stresses in a Deck Pavement with an Interlayer Contact Model
Random surface roughness of bridge deck pavement just like random road surface roughness was simulated by the harmony superposition method in this paper.
Xuntao Wang +5 more
doaj +1 more source
New surface plasmon polariton waveguide based on GaN nanowires
Lasers are nowadays widely used in industry, in hospitals and in many devices that we have at home. Random laser development is challenging given its high threshold and low integration.
Jun Zhu +4 more
doaj +1 more source
Frictional Characteristic Curves of Ground Surfaces in Lubricated Sliding
The key objective of the presented study was to use a commercially feasible and scalable approach to modifying surfaces to reduce friction. In an industrial setting, surface grinding is commercially viable and scalable as compared to other surface ...
Gopakumar Parameswaran +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Analysis of surface roughness in relation to soil loss and runoff at high rainfall intensities. [PDF]
The decay of roughness is an important factor governing surface processes such as infiltration and soil erosion. Thus the decay of surface roughness under different surface conditions was investigated and related to quantitative amounts of soil loss ...
Idowu, O. J. +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

