Results 41 to 50 of about 667,561 (138)

Factors influencing participation in randomised clinical trials among patients with early Barrett's neoplasia: a multicentre interview study [PDF]

, 2023
OBJECTIVES: Strong recruitment and retention into randomised controlled trials involving invasive therapies is a matter of priority to ensure better achievement of trial aims. The BRIDE (Barrett's Randomised Intervention for Dysplasia by Endoscopy) Study
Barr, Hugh, Bhandari, Pradeep, De Caestecker, John, Haidry, Rehan, Jackson, Clare, Lovat, Laurence B, Peerally, Mohammad Farhad, Ragunath, Krish, Smart, Howard, Stokes, Clive   +9 more
core  

Design Considerations for a Phase II platform trial in Major Depressive Disorder [PDF]

arXiv, 2023
Major Depressive Disorder (MDD) is one of the most common causes of disability worldwide. Unfortunately, about one-third of patients do not benefit sufficiently from available treatments and not many new drugs have been developed in this area in recent years.
arxiv  

Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over [PDF]

, 2018
Background: Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypothyroidism in persons aged 80 ...
Blum, M.R., Dekkers, O.M., Den Elzen, W.P.J., Du Puy, R.S., Ford, I., Gussekloo, J., Jukema, J.W., Kean, S., Kearney, P.M., Messow, C.M., Mooijaart, S.P., Peeters, R.P., Poortvliet, R.K.E., Postmus, I., Rodondi, N., Smit, J.W.A., Stott, D.J., van Munster, B.C., Watt, T., Westendorp, R.G.J., Wolffenbuttel, B.H.R.   +20 more
core   +7 more sources

Conceptualising Natural and Quasi Experiments in Public Health [PDF]

, 2020
Background: Natural or quasi experiments are appealing for public health research because they enable the evaluation of events or interventions that are difficult or impossible to manipulate experimentally, such as many policy and health system reforms.
arxiv   +1 more source

A systematic review of randomised controlled trials on the effectiveness of exercise programs on lumbo pelvic pain among postnatal women [PDF]

, 2015
Background: A substantial number of women tend to be affected by Lumbo Pelvic Pain (LPP) following child birth. Physical exercise is indicated as a beneficial method to relieve LPP, but individual studies appear to suggest mixed findings about its ...
A Garshasbi, A Gutke, A Gutke, A Gutke, A Gutke, A Tanvi, A Vleeming, AB Granath, AG Cramp, B Stuge, B Stuge, C Richardson, CB Olsson, CB Olsson, CD Skaggs, CF Yan, CG Maher, DB Stapleton, E Kontopantelis, E Líndal, E Thorell, EC Larsen, EK Bjelland, HM McCormack, HS Robinson, HS Robinson, HY Chang, I Mogren, IM Mogren, J Walker, JM Kendall, JM Mens, JM Mens, K Björklund, K Gjestland, L Nilsson-Wikmar, L Nilsson‐Wikmar, L Norén, M Kumle, M Perry, MA Mohseni-Bandpei, Meei-Ling Gau, NA Al‐Sayegh, NC Foley, NK Vøllestad, NN Ansari, O Airaksinen, O Ayanniyi, Pei-Ching Tseng, S Chaudry, S Malmqvist, SA Olivo, Shuby Puthussery, SM Wang, WWK To, Y Ko, Yannis Pappas, YL Ko   +57 more
core   +1 more source

Quantifying efficiency gains of innovative designs of two-arm vaccine trials for COVID-19 using an epidemic simulation model [PDF]

arXiv, 2021
Clinical trials of a vaccine during an epidemic face particular challenges, such as the pressure to identify an effective vaccine quickly to control the epidemic, and the effect that time-space-varying infection incidence has on the power of a trial.
arxiv  

Permutation-based multiple testing corrections for p-values and confidence intervals for cluster randomised trials [PDF]

arXiv, 2021
In this article, we derive and compare methods to derive \textit{p}-values and sets of confidence intervals with strong control of the family-wise error rates and coverage for estimates of treatment effects in cluster randomised trials with multiple outcomes.
arxiv  

Suggested randomised, controlled trial with frovatriptan [PDF]

The Journal of Headache and Pain, 2011
Sir, Frovatriptan versus other treatments for acute migraine There are now three crossover, double-blind, randomized controlled trials (RCTs) of similar design comparing frovatriptan 2.5 mg with zolmitriptan 2.5 mg [1], rizatriptan 10 mg [2] and almotriptan 12.5 mg [3].
Peer Tfelt-Hansen, Timothy J. Steiner
openaire   +3 more sources

Regaining Confidence after Stroke (RCAS): a feasibility randomised controlled trial (RCT) [PDF]

, 2019
Background: The Regaining Confidence after Stroke Course (RCAS) was designed to facilitate adjustment for people with stroke discharged from rehabilitation.
Hooban, Kate E., Horne, Jane C., Lincoln, Nadina B., Logan, Pip   +3 more
core   +2 more sources

A randomised controlled trial to compare the clinical and cost-effectiveness of prism glasses, visual search training and standard care in patients with hemianopia following stroke: a protocol [PDF]

, 2014
INTRODUCTION: Homonymous hemianopia is a common and disabling visual problem after stroke. Currently, prism glasses and visual scanning training are proposed to improve it.
Barrett, Black, Bouwmeester, Bowers, Department of Health, Dombovy, Giorgi, Gray, Jones, Jongbloed, Kaplan, Kerkhoff, Lancaster, Machin, Pambakian, Peli, Pollock, Pollock, Pollock, Ramrattan, Riggs, Rossi, Rowe, Rowe, Rowe, Royal College of Physicians Intercollegiate Stroke Working Party, Schofield   +26 more
core   +2 more sources