On Preparing a List of Random treatment Assigns [PDF]
arXiv, 2015 This paper presents the foundations of a computer oriented approach for preparing a list of random treatment assignments to be adopted in randomised controlled trials. Software is presented which can be applied in the earliest stage of clinical trials and bioequivalence assays. This allocation of patients to treatment in clinical trials ensures exactly
arxiv
Acupuncture in Seasonal Allergic Rhinitis (ACUSAR) - Design and Protocol of a Randomised Controlled Multi-Centre Trial [PDF]
, 2010 Background: We report on the study design and protocol of a randomised controlled trial (Acupuncture in Seasonal Allergic Rhinitis, ACUSAR) that investigates the efficacy of acupuncture in the treatment of seasonal allergic rhinitis (SAR).
Brinkhaus, Benno +11 more
core +1 more source
Understanding randomised controlled trials [PDF]
Archives of Disease in Childhood, 2005 The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled trial, is discussed. Issues that need to be considered during the critical appraisal of randomised controlled trials, such as assessing the validity of ...
openaire +3 more sources
An optimised patient information sheet did not significantly increase recruitment or retention in a falls prevention study: an embedded randomised recruitment trial [PDF]
, 2017 \ua9 2017 The Author(s).Background: Randomised controlled trials are generally regarded as the \u27gold standard\u27 experimental design to determine the effectiveness of an intervention.
Adamson J +21 more
core +1 more source
Supported employment: randomised controlled trial [PDF]
British Journal of Psychiatry, 2010 BackgroundThere is evidence from North American trials that supported employment using the individual placement and support (IPS) model is effective in helping individuals with severe mental illness gain competitive employment. There have been few trials in other parts of the world.AimsTo investigate the effectiveness and cost-effectiveness of IPS in ...
Howard, Louise M. +8 more
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Robustness of ANCOVA in randomised trials with unequal randomisation [PDF]
arXiv, 2019 Randomised trials with continuous outcomes are often analysed using ANCOVA, with adjustment for prognostic baseline covariates. In an article published recently, Wang \etal proved that in this setting the model based standard error estimator for the treamtent effect is consistent under outcome model misspecification, provided the probability of ...
arxiv
Automated Extraction of Number of Subjects in Randomised Controlled Trials [PDF]
arXiv, 2016 We present a simple approach for automatically extracting the number of subjects involved in randomised controlled trials (RCT). Our approach first applies a set of rule-based techniques to extract candidate study sizes from the abstracts of the articles.
arxiv
Writing to patients: a randomised controlled trial [PDF]
Clinical Medicine, 2006 It has been suggested that consultants should consider writing directly to patients with a summary of their outpatient consultation. In a controlled trial involving consecutive new referrals to a haematology outpatient clinic, we randomised patients to receive either a personal letter from their consultant summarising their consultation (n = 77) or a ...
O'Reilly, Máire +2 more
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Effect of a machine learning-based severe sepsis prediction algorithm on patient survival and hospital length of stay: a randomised clinical trial. [PDF]
, 2017 IntroductionSeveral methods have been developed to electronically monitor patients for severe sepsis, but few provide predictive capabilities to enable early intervention; furthermore, no severe sepsis prediction systems have been previously validated in
Barton, Christopher W +4 more
core +2 more sources
Maximising the impact of qualitative research in feasibility studies for randomised controlled trials: guidance for researchers [PDF]
, 2015 Feasibility studies are increasingly undertaken in preparation for randomised controlled trials in order to explore uncertainties and enable trialists to optimise the intervention or the conduct of the trial.
Adamson, J. +9 more
core +2 more sources