Results 51 to 60 of about 698,130 (312)
The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek +59 morewiley +1 more sourceEnteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT
Health Technology Assessment, 2018 Background: Infections acquired in hospital are an important cause of morbidity and mortality in very preterm infants. Several small trials have suggested that supplementing the enteral diet of very preterm infants with lactoferrin, an antimicrobial ...James Griffiths, Paula Jenkins, Monika Vargova, Ursula Bowler, Edmund Juszczak, Andrew King, Louise Linsell, David Murray, Christopher Partlett, Mehali Patel, Janet Berrington, Nicholas Embleton, Jon Dorling, Paul T Heath, William McGuire, Sam Oddie +15 moredoaj +1 more sourceUndertaking a randomised controlled trial in the police setting : methodological and practical challenges [PDF]
, 2017 BACKGROUND: There has been an increased drive towards Evidence Based Policing in recent years. Unlike in other public sector services, such as health and education, randomised controlled trials in the police setting are relatively rare.Booth, Alison, Fairhurst, Caroline, Hewitt, Catherine, McDaid, Catriona, Parker, Adwoa, Payne, Rebecca, Reed, Helen, Scantlebury, Arabella, Scott, William J, Torgerson, David +9 morecore +2 more sourcesStressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction
Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods
Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster +13 morewiley +1 more sourceSchool-based group interpersonal therapy for adolescents with depression in Nepal: protocol for a phase III realist cluster-randomised controlled trial
BMC PsychiatryBackground Depression is a leading cause of disability among adolescents, with the burden disproportionately affecting low- and middle-income countries (LMICs) where access to mental health care is limited.Kelly Rose-Clarke, Cemile Ceren Sonmez, Sujan Shrestha, Bishnu Lamichhane, Indira Pradhan, Parbati Pandey, Pratima Kandel, John Hodsoll, Lauren Yan, Bryan Patenaude, Helen Verdeli, Kamal Gautam, Mark Jordans, Chris Bonell, Nagendra P. Luitel +14 moredoaj +1 more sourceFacilitating return to work through early specialist health-based interventions (FRESH): protocol for a feasibility randomised controlled trial [PDF]
, 2015 Background
Over one million people sustain traumatic brain injury each year in the UK and more than 10 % of these are moderate or severe injuries, resulting in cognitive and psychological problems that affect the ability to work.A Franulic, A Relyea-Chew, A Tyerman, AH Briggs, AH Willemse-van Son, AM Salazar, AS Zigmond, B Robinson, B Willer, British Society of Rehabilitation Medicine, E Rickels, F Nouri, J Langley, J Phillips, J Possl, JK Fadyl, JM Velzen Van, JM Velzen van, JN Horton, KA Radford, LE Trexler, MC Reilly, P Deshpande, R Brooks, RD Vanderploeg, S Schonbrun, T Ownsworth +26 morecore +5 more sourcesExploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction
Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine +10 morewiley +1 more sourceOndansetron for irritable bowel syndrome with diarrhoea: randomised controlled trial
Efficacy and Mechanism Evaluation, 2023 Background Irritable bowel syndrome with diarrhoea is characterised by frequent, loose or watery stools with associated urgency, resulting in marked reduction of quality of life. Ondansetron, a 5-hydroxytryptamine-3 receptor antagonist, has been shown to David Gunn, Rabia Topan, Ron Fried, Ivana Holloway, Richard Brindle, Suzanne Hartley, Lorna Barnard, Maura Corsetti, S Mark Scott, Adam Farmer, Ayesha Akbar, Maria Eugenicos, Nigel Trudgill, Kapil Kapur, John McLaughlin, David S Sanders, Arvind Ramadas, Peter Whorwell, Lesley Houghton, Phil G Dinning, Qasim Aziz, Alexander C Ford, Amanda Farrin, Robin Spiller +23 moredoaj +1 more sourceThe CEA Second-Look Trial: a randomised controlled trial of carcinoembryonic antigen prompted reoperation for recurrent colorectal cancer [PDF]
, 2014 Objective In patients who have undergone a potentially curative resection of colorectal cancer, does a ‘second-look’ operation to resect recurrence, prompted by monthly monitoring of carcinoembryonic antigen, confer a survival benefit?Design A randomised Bacon, Cochrane, Doshi, Ekman, Ellis, Embun, Fiorentino, Fiorentino, Fiorentino, Gill, Goldenberg, Grunhagen, Horton, Keep, Kraemer, Lennon, Levesque, Lewis, Loder, Mach, Mackay, Martin, Martin, Meeker, Moertel, Morris, Nicholson, Northover, Polk, Poston, Primrose, Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2, Rosen, Searle, Staab, Treasure, Treasure, Treasure, Treasure, Utley, Wangensteen, Welch +41 morecore +1 more sourceThe Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini +20 morewiley +1 more source
