Results 41 to 50 of about 8,079,813 (317)

Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial. [PDF]

, 2012
BACKGROUND: The purpose of this research is to develop and evaluate methods for conducting pragmatic cluster randomized trials in a primary care electronic database.
Wolfe Charles, Van Staa, Tjeerd; id_orcid, van Staa, Tjeerd, Mcdermott Lisa, Judith Charlton, Gulliford, Martin, Gerard McCann, Charlton, Judith, Ashworth Mark, Ashworth, Mark, Dregan Alex, McCann, Gerard, Charlton Judith, Anthony Rudd, Rudd Anthony, Lucy Yardley, Mark Ashworth, Gulliford Martin, Dregan, Alex; id_orcid, McCann Gerard, Lisa Mcdermott, Martin Gulliford, Tjeerd van Staa, Dregan, Alex, Yardley, Lucy, ?, ?, McDermott, Lisa, van Staa Tjeerd, null null, Wolfe, Charles, Yardley Lucy, Rudd, Anthony, eCRT Research Team, Charles Wolfe, Alex Dregan   +34 more
core   +2 more sources

Electromyogram-Biofeedback in Patients with Fibromyalgia A Randomized Controlled Trial [PDF]

, 2009
Electromyogram-Biofeedback in Patients with Fibromyalgia: A Randomized Controlled Trial Objective: To evaluate the effectiveness of EMG-biofeedback in patients with Fibromyalgia.
Baumueller, Eva
core   +1 more source

Efficacy of ozonated water and chlorhexidine mouth rinse against plaque and gingivitis: A randomized clinical trial

Journal of Clinical Sciences, 2017
Aim: The aim of this study was to compare the efficacy of ozonated water and chlorhexidine mouth rinse against plaque and gingivitis. Materials and Methods: A randomized, double-blind clinical trial was conducted.
Sujal Mitul Parkar, Kanchi Shah, Nikhil Darjee, Abhishek Sharma   +3 more
doaj   +1 more source

Three drug combinations for late-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Uganda. [PDF]

, 2006
OBJECTIVES: Our objective was to compare the efficacy and safety of three drug combinations for the treatment of late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Louga, Albino, Fogg Carole, Louga Albino, Ghabri, S, Piola, P, Piola, Patrice, Balasegaram, M, Checchi Francesco, Balasegaram, Manica, Priotto Gerardo, Louga, A, Checchi, F, Priotto, Gerardo, Priotto, G, Erphas, Olema, Checchi, Francesco, Ghabri, Salah, Erphas, O, Balasegaram Manica, Ghabri Salah, Erphas Olema, Fogg, C, Fogg, Carole, Piola Patrice   +23 more
core   +1 more source

Estimating vaccine efficacy during open-label follow-up of COVID-19 vaccine trials based on population-level surveillance data

Epidemics
While rapid development and roll out of COVID-19 vaccines is necessary in a pandemic, the process limits the ability of clinical trials to assess longer-term vaccine efficacy. We leveraged COVID-19 surveillance data in the U.S.
Mia Moore, Yifan Zhu, Ian Hirsch, Tom White, Robert C. Reiner, Ryan M. Barber, David Pigott, James K. Collins, Serena Santoni, Magdalena E. Sobieszczyk, Holly Janes   +10 more
doaj   +1 more source

Manual acupuncture as prophylaxis for migraine without aura: study protocol for a multi-center, randomized, single-blinded trial

Trials, 2022
Background Migraine is a highly prevalent neurological disorder. It is the third most prevalent disorder and the seventh highest cause of disability worldwide.
Jiao Chen, Siyuan Zhou, Mingsheng Sun, Yanan Wang, Xiaoqin Chen, Taipin Guo, Lu Liu, Jing Luo, Xixiu Ni, Xuguang Yang, Dehua Li, Shan Gao, Zhenxi He, Dingjun Cai, Ling Zhao   +14 more
doaj   +1 more source

Strategies used for the COVID-OUT decentralized trial of outpatient treatment of SARS-CoV-2

Journal of Clinical and Translational Science, 2023
The COVID-19 pandemic accelerated the development of decentralized clinical trials (DCT). DCT’s are an important and pragmatic method for assessing health outcomes yet comprise only a minority of clinical trials, and few published methodologies exist. In
Nandini Avula, Dustin Kakach, Christopher J. Tignanelli, David M. Liebovitz, Jacinda M. Nicklas, Kenneth Cohen, Michael A. Puskarich, Hrishikesh K. Belani, John B. Buse, Nichole R. Klatt, Blake Anderson, Amy B. Karger, Katrina M. Hartman, Barkha Patel, Sarah L. Fenno, Neha V. Reddy, Spencer M. Erickson, David R. Boulware, Thomas A. Murray, Carolyn T. Bramante, COVID-OUT Trial Team   +20 more
doaj   +1 more source

Acupuncture for chronic knee pain: a randomized clinical trial. [PDF]

, 2014
IMPORTANCE: There is debate about benefits of acupuncture for knee pain. OBJECTIVE: To determine the efficacy of laser and needle acupuncture for chronic knee pain.
McCrory, Paul, Williamson, Elizabeth, McCrory, P, Hinman, R S, Reddy, P, Reddy, Prasuna, Metcalf, B R, Bennell, KL, Metcalf, BR, Conaghan, P G, Pirotta, M, Relf, I, Crossley, K M, Crossley, Kay M, Kyriakides, Mary, Metcalf, Ben R, Bennell, Kim L, Kyriakides, M, Conaghan, PG, Novy, Kitty, Bennell, K L, Crossley, KM, Conaghan, Philip G, Harris, Anthony, Hinman, RS, Williamson, E, Novy, K, Harris, A, Hinman, Rana S, Relf, Ian, Forbes, A, Pirotta, Marie, Forbes, Andrew   +32 more
core   +1 more source

Positive predictive value of respiratory infection diagnoses in the Danish National Patient Registry: A post hoc validation analysis of the DANFLU-1 trial

International Journal of Infectious Diseases
Objectives: To validate respiratory infection diagnosis codes in the Danish National Patient Registry (DNPR) in the DANFLU-1 feasibility trial, and to assess whether reperforming effectiveness analyses with validated events altered findings.
Jacob Christensen, Niklas Dyrby Johansen, Katrine Feldballe Bernholm, Julie Inge-Marie Helene Borchsenius, Kira Hyldekær Janstrup, Daniel Modin, Kristoffer Grundtvig Skaarup, Joshua Nealon, Sandrine Samson, Matthew Loiacono, Youjun Huang, Rebecca Harris, Carsten Schade Larsen, Anne Marie Reimer Jensen, Nino Emanuel Landler, Brian L. Claggett, Scott D. Solomon, Gunnar H. Gislason, Lars Køber, Martin J. Landray, Pradeesh Sivapalan, Jens Ulrik Stæhr Jensen, Tor Biering-Sørensen   +22 more
doaj   +1 more source

Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm. [PDF]

, 2013
BACKGROUND: Single-centre series of the management of patients with ruptured abdominal aortic aneurysm (AAA) are usually too small to identify clinical factors that could improve patient outcomes.
Hinchliffe, RJ, Thompson, MM, Bell, R, Greenhalgh, R. M., Ashleigh, R., Grieve, RJ, Ulug, P., Heatley, F., Powell, JT, Sweeting, M. J., Ashleigh, R, Heatley, F, Thompson, S. G., Powell, J. T., Greenhalgh, RM, Gomes, M, Ulug, P, Sweeting, MJ, Gomes, M., ?, ?, Thompson, SG, Hinchliffe, R. J., IMPROVE trial investigators, Thompson, M. M., Bell, Rachel, Grieve, R. J.   +25 more
core   +1 more source