Results 11 to 20 of about 4,375,535 (213)

Randomized controlled trials in neurosurgery

Surgical Neurology International, 2022
Randomized controlled trials (RCTs) have become the standard method of evaluating new interventions (whether medical or surgical), and the best evidence used to inform the development of new practice guidelines. When we review the history of medical versus surgical trials, surgical RCTs usually face more challenges and difficulties when conducted ...
Takroni, Radwan, Sharma, Sunjay, Reddy, Kesava, Zagzoog, Nirmeen, Aljoghaiman, Majid, Alotaibi, Mazen, Farrokhyar, Forough   +6 more
openaire   +2 more sources

Analysis of Randomized Controlled Trials [PDF]

Epidemiologic Reviews, 2002
Although the sophistication and flexibility of the statistical technology available to the data analyst have increased, some durable, simple principles remain valid. Hypothesis-driven analyses, which were anticipated and specified in the protocol, must still be kept separate and privileged relative to the important, but risky data mining made possible ...
Peter, Peduzzi, William, Henderson, Pamela, Hartigan, Philip, Lavori   +3 more
openaire   +2 more sources

PRECAF Randomized Controlled Trial [PDF]

Circulation: Arrhythmia and Electrophysiology, 2021
Background: We have previously shown that the presence of dual muscular coronary sinus (CS) to left atrial (LA) connections, coupled with rate-dependent unidirectional block in one limb, is associated with atrial fibrillation (AF) induction. This study sought to examine whether ablation of distal CS to LA connections at a first
Ling Kuo, David S. Frankel, Aung Lin, Jeffrey Arkles, Matthew Hyman, Pasquale Santangeli, Francis E. Marchlinski, Saman Nazarian   +7 more
openaire   +2 more sources

Mental practice with motor imagery in stroke recovery: randomized controlled trial of efficacy [PDF]

, 2011
This randomized controlled trial evaluated the therapeutic benefit of mental practice with motor imagery in stroke patients with persistent upper limb motor weakness.
Scott, Clare L, Sara Joice, Clare L. Scott, Marie Johnston, Ietswaart, Magdalena, Dijkerman, H Chris, Scott, Claire, H. Chris Dijkerman, Dijkerman, H. Chris, Steven J.C. Hamilton, MacWalter, Ronald, Hamilton, Steven, MacWalter, Ronald S., Johnston, Marie, Magdalena Ietswaart, MacWalter, Ronald S, Ronald S. MacWalter, Joice, Sara, Scott, Clare L., Hamilton, Steven J. C., Hamilton, Steven J C   +20 more
core   +1 more source

Three controlled trials of interventions to increase recruitment to a randomized controlled trial of mobile phone based smoking cessation support. [PDF]

, 2010
BACKGROUND: Recruitment is a major challenge for trials but there is little evidence regarding interventions to increase trial recruitment. We report three controlled trials of interventions to increase recruitment to the Txt2stop trial.
Free, Caroline, Robertson, Steven, Knight, Rosemary, Hoile, Elizabeth   +3 more
core   +1 more source

Clinical Research Using Salviae Miltiorrhizae Radix-Pharmacopuncture for Lumbar Herniated Intervertebral Disc: Analysis of Trends [PDF]

Journal of Acupuncture Research, 2021
This review of national and international randomized controlled trials of Salviae miltiorrhizae radix pharmacopuncture for lumbar herniated intervertebral discs was performed to assess its clinical efficacy. There were 5 online databases (PubMed, EMBASE,
Seon Woo Kim, Cheol Woo Park, Myeong Jae Jo, Min Wook Kim, Jae Hee Yu, Jeon Seok Hee, Seung Won Jang, Do Young Kang, Hyun Jin Jeong   +8 more
doaj   +1 more source

The effectiveness of alcohol screening and brief intervention in emergency departments: A multicentre pragmatic cluster randomized controlled trial [PDF]

, 2014
Background Alcohol misuse is common in people attending emergency departments (EDs) and there is some evidence of efficacy of alcohol screening and brief interventions (SBI).
Patton, Robert, Dale, V, Eileen Kaner (588847), Deluca Paolo, Drummond, Colin, Gilvarry Eilish, Eilish Gilvarry (588836), Newbury-Birch, Dorothy, Touquet Robin, Judy Myles (588839), Martin Bland (222260), Colin Drummond (339336), Mike Crawford, Cassidy, P, Deluca, Paolo; id_orcid, Patton, R, Bland, Martin, Shepherd Jonathan, Newbury-Birch Dorothy, Eileen Kaner, Adenekan Oyefeso, Myles Judy, Steve Parrott, Heather, Nick, Oyefeso, Adenekan, Parrott, Steve, Colin Drummond, Ruth McGovern, Katherine Perryman, Coulton, S, Patton Robert, Nick Heather (588837), Perryman, K, Paolo Deluca, Steve Parrott (588841), Dorothy Newbury-Birch (588840), Dale, Veronica, Myles, J, Cassidy, Paul, Tom Phillips, Godfrey Christine, Kaner, E, Newbury-Birch, D, Oyefeso, A, Cassidy Paul, Simon Coulton, Robin Touquet (588846), Drummond Colin, Heather Nick, Veronica Dale (588835), Jonathan Shepherd (588845), McGovern Ruth, Oyfeso, Adenekan, Touquet, R, Perryman Katherine, Shepherd, Jonathan, Parrott, S, Phillips, T, Veronica Dale, Paolo Deluca (588833), Christine Godfrey (227956), Paul Cassidy (588834), Ruth McGovern (588838), Adenekan Oyefeso (18454), Godfrey, Christine, Myles, Judy, Jonathan Shepherd, Robin Touquet, Parrott Steve, Christine Godfrey, Perryman, Katherine, Phillips, Tom, Oyefeso Adenekan, Katherine Perryman (588843), Tom Phillips (588844), Judy Myles, Drummond, C, Heather, N, Deluca, Paolo, Coulton, Simon, Coulton Simon, Kaner Eileen, Simon Coulton (167071), Newbury-Birch, Dorothy; id_orcid, Drummond, Colin; id_orcid, Nick Heather, Phillips Tom, Crawford, M, Dorothy Newbury-Birch, Mike Crawford (282626), Bland Martin, Crawford Mike, Dale Veronica, Touquet, Robin, Gilvarry, Eilish, Kaner, Eileen, Robert Patton (588842), McGovern, Ruth, McGovern, R, Patton, Bob, Martin Bland, Crawford, Mike, Torquet, Robin, Robert Patton, Shepherd, J, Philips, Tom, Gilvarry, E, Eilish Gilvarry, Deluca, P, Godfrey, C, Paul Cassidy, Bland, M   +111 more
core   +1 more source

CONSORT for Reporting Randomized Controlled Trials in Journal and Conference Abstracts: Explanation and Elaboration [PDF]

, 2008
BACKGROUND: Clear, transparent, and sufficiently detailed abstracts of conferences and journal articles related to randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the ...
Hopewell, S, Douglas G Altman, Moher, D., Mike Clarke, Schulz, KF, Hopewell, S., Wager, E., Philippa Middleton, The, CG, Sally Hopewell, Schulz, K., Moher, D, Altman, DG, CONSORT Group, Middleton, P, Clarke, M., Hopewel, S, Kenneth F Schulz, Elizabeth Wager, Wager, E, Middleton, P., Hopewell, Sally, David Moher, Altman, D., null null, Clarke, Michael, Clarke, M   +26 more
core   +1 more source

A Randomized Double-blind Controlled Trial of Lactobacillus acidophilus Plus Bifidobacterium bifidum versus Placebo in Patients with Hypercholesterolemia [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Hypercholesterolemia is a major risk factor for cardiovascular disease. Not all patients respond well to traditional cholesterol lowering medications.
Sanguansak Rerksuppaphol, Lakkana Rerksuppaphol   +1 more
doaj   +1 more source

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]

, 2012
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
O'Kane, Cecilia M., O’Kane, Cecilia M., Laffey, John G, Cross, Mark, John G Laffey, McAuley, Daniel F; id_orcid, McNally, Christine, Michael Stevenson, Perkins, Gavin D., Crealey, Grainne, Laffey, John G., Daniel F McAuley, Murphy, Lynn, HASH(0x55a67ff73468), Stevenson, Michael, Cross, L. J. Mark, Grainne Crealey, Cecilia M O’Kane, McAuley, Daniel F., Mark Cross, null null, Gavin D Perkins, Perkins, Gavin D, Christine McNally, Lynn Murphy, O'Kane, Cecilia M, Cross Mark, Stevenson Michael, Murphy Lynn, McNally Christine, Crealey Grainne, Laffey John G, O’Kane Cecilia M, McAuley Daniel F, Perkins Gavin D   +34 more
core   +2 more sources