Results 21 to 30 of about 1,017,967 (316)

Necessity of pharyngeal anesthesia during transoral gastrointestinal endoscopy: a randomized clinical trial [PDF]

Clinical Endoscopy, 2023
Background/Aims The necessity for pharyngeal anesthesia during upper gastrointestinal endoscopy is controversial. This study aimed to compare the observation ability with and without pharyngeal anesthesia under midazolam sedation.
Tomoyuki Hayashi, Yoshiro Asahina, Yasuhito Takeda, Masaki Miyazawa, Hajime Takatori, Hidenori Kido, Jun Seishima, Noriho Iida, Kazuya Kitamura, Takeshi Terashima, Sakae Miyagi, Tadashi Toyama, Eishiro Mizukoshi, Taro Yamashita   +13 more
doaj   +1 more source

Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]

, 2008
This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Norton, C., Parés, D., Chelvanayagam, Sonya   +2 more
core   +1 more source

Acceptance and Commitment Therapy group for treatment-resistant participants: a randomized controlled trial [PDF]

, 2014
Acceptance and Commitment Therapy (ACT) is a theoretically coherent approach addressing common processes across a range of disorders. The aim of this study was to investigate the effectiveness of a group-based ACT intervention for ‘treatment-resistant ...
Clarke, Sue, James, Kirsty, Remington, Bob, Remington, B., James, K., Kingston, Jessica, Kingston, J., Bolderston, Helen   +7 more
core   +1 more source

Two controlled trials to increase participant retention in a randomized controlled trial of mobile phone-based smoking cessation support in the United Kingdom. [PDF]

, 2011
BACKGROUND: Loss to follow-up of trial participants represents a threat to research validity. To date, interventions designed to increase participants' awareness of benefits to society of completing follow-up, and the impact of a telephone call from a ...
Free, Caroline, Rosemary Knight, Caroline Free, Edwards, Philip, Ettore Severi, Robertson, Steven, Severi, Ettore, Steven Robertson, Knight, Rosemary, Elizabeth Hoile, Philip Edwards, Hoile, Elizabeth   +11 more
core   +1 more source

Design of Randomized Controlled Trials [PDF]

Circulation, 2007
A major factor in the rapid advance of medical science over the past 50 years has been the development and refinement of the clinical research method known as the randomized controlled trial (RCT). A clinical trial is defined as a prospective scientific experiment that involves human subjects in whom treatment is initiated for the evaluation of a ...
openaire   +2 more sources

Interpreting Randomized Controlled Trials

Cancers, 2023
This article describes rationales and limitations for making inferences based on data from randomized controlled trials (RCTs). We argue that obtaining a representative random sample from a patient population is impossible for a clinical trial because patients are accrued sequentially over time and thus comprise a convenience sample, subject only to ...
Pavlos Msaouel, Juhee Lee, Peter F Thall
openaire   +2 more sources

Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]

, 2012
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Matthew W Cooke, Patel, Jaimin M, Thickett, David R, David R Thickett, Alan Jones, Anthony H Barnett, Hawkey, P. M., Jaimin M Patel, Catherine Snaith, Perkins, Gavin D., Smith, F. Gao, Jones, Alan, Gao Smith, Fang; id_orcid, Fang Gao, Linhartova, Lucie, Snaith, Catherine, Hong, Tan, Gao, Fang, Tan Hong, Lucie Linhartova, Hawkey, Peter, Peter Hawkey, Cooke, Matthew W, Thickett, David R; id_orcid, Barnett, Anthony H, Cooke, Matthew, Barnett, A. H., Gavin D Perkins, Melody, Teresa, Perkins, Gavin D, Patel, Jaimin M., Thickett, David R., Teresa Melody   +32 more
core   +1 more source

The external validity of published randomized controlled trials in primary care [PDF]

, 2009
Background - A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population.
Jones Robert O, McCowan, Colin, Jones, R, Colin McCowan (434192), McCowan, C, Fahey, T., Jones, Robert O., Colin McCowan, Montgomery, AA, Fahey Tom, Jones, RO, Fahey, T, McCowan Colin, Alan A Montgomery, Montgomery Alan A, Jones Ritu, Fahey, Thomas, Robert O Jones, Ritu Jones (7944167), Tom Fahey (7896266), Robert O. Jones (7944170), Alan A. Montgomery (7705694), Tom Fahey, Ritu Jones, Mccowan, C., Montgomery, A.A., Jones, R.O., Montgomery, Alan A., Jones, R., Jones, Ritu   +29 more
core   +1 more source

The Effect of Acupressure on Fasting Blood Glucose and Glycosylated Hemoglobin Levels in Diabetic Patients: A Randomized Controlled Trial [PDF]

International Journal of Community Based Nursing and Midwifery, 2021
Background: Diabetes is the most common endocrine disorder. Non-pharmacological methodscan be used for treatment of these patients. The present study aimed to investigate the effect ofacupressure point on fasting blood glucose and glycosylated levels of ...
Sied Najafi, Hassan Ghorbani, Amin Kordi Yoosefinejad, Majid Najafi Kalyani   +3 more
doaj   +1 more source

The cessation in pregnancy incentives trial (CPIT): study protocol for a randomized controlled trial [PDF]

, 2012
Background: Seventy percent of women in Scotland have at least one baby, making pregnancy an opportunity to help most young women quit smoking before their own health is irreparably compromised.
De Caestecker, L., Boyd Kathleen, Liz Grant, Bauld Linda, Tappin, David, Sinclair, Lesley, Grant, Liz, Friel, Brenda, Radley, Andrew, Linda de Caestecker, Radley, Andrew; id_orcid, MacAskill Susan, Tannahill, Carol, Cameron, Alan, Carol Tannahill, Coleman, T., Susan MacAskill, Boyd, K., Coleman Tim, Coleman, Tim, McConnachie, A., Sinclair Lesley, Cameron Alan, Radley, A., Briggs, Andrew, McConnachie, Alex, Tappin David M, Briggs Andrew, Tim Coleman, Tannahill Carol, Radley Andrew, Macaskill, S., Lesley Sinclair, Tannahill, C., Kathleen Boyd, Andrew Briggs, Cameron, A., MacAskill, Susan, Friel, B., David M Tappin, Bauld, L., Tappin, D.M., McConnachie Alex, Alex McConnachie, de Caestecker Linda, Briggs, A., Bauld, Linda, de Caestecker, Linda, Sinclair, L., Boyd, Kathleen, Friel Brenda, Andrew Radley, Tappin, David M., Linda Bauld, Brenda Friel, Grant, L., Grant Liz, Alan Cameron   +57 more
core   +1 more source