Results 21 to 30 of about 4,658,408 (267)

Clinical Research Using Salviae Miltiorrhizae Radix-Pharmacopuncture for Lumbar Herniated Intervertebral Disc: Analysis of Trends [PDF]

Journal of Acupuncture Research, 2021
This review of national and international randomized controlled trials of Salviae miltiorrhizae radix pharmacopuncture for lumbar herniated intervertebral discs was performed to assess its clinical efficacy. There were 5 online databases (PubMed, EMBASE,
Seon Woo Kim, Cheol Woo Park, Myeong Jae Jo, Min Wook Kim, Jae Hee Yu, Jeon Seok Hee, Seung Won Jang, Do Young Kang, Hyun Jin Jeong   +8 more
doaj   +1 more source

The external validity of published randomized controlled trials in primary care [PDF]

, 2009
Background - A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population.
Jones Robert O, McCowan, Colin, Jones, R, Colin McCowan (434192), McCowan, C, Fahey, T., Jones, Robert O., Colin McCowan, Montgomery, AA, Fahey Tom, Jones, RO, Fahey, T, McCowan Colin, Alan A Montgomery, Montgomery Alan A, Jones Ritu, Fahey, Thomas, Robert O Jones, Ritu Jones (7944167), Tom Fahey (7896266), Robert O. Jones (7944170), Alan A. Montgomery (7705694), Tom Fahey, Ritu Jones, Mccowan, C., Montgomery, A.A., Jones, R.O., Montgomery, Alan A., Jones, R., Jones, Ritu, Mccowan, C.; id_orcid   +30 more
core   +2 more sources

Malaria positivity following a single oral dose of azithromycin among children in Burkina Faso: a randomized controlled trial

BMC Infectious Diseases, 2022
Background Azithromycin is a broad-spectrum antibiotic that has moderate antimalarial activity and has been shown to reduce all-cause mortality when biannually administered to children under five in high mortality settings in sub-Saharan Africa.
Jessica Brogdon, Clarisse Dah, Ali Sié, Mamadou Bountogo, Boubacar Coulibaly, Idrissa Kouanda, Mamadou Ouattara, Guillaume Compaoré, Eric Nebie, Mariam Seynou, Elodie Lebas, Fanice Nyatigo, Huiyu Hu, Benjamin F. Arnold, Thomas M. Lietman, Catherine E. Oldenburg   +15 more
doaj   +1 more source

An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial. [PDF]

, 2014
BACKGROUND: Organ dysfunction consequent to infection ('severe sepsis') is the leading cause of admission to an intensive care unit (ICU). In both animal models and early clinical studies the calcium channel sensitizer levosimendan has been demonstrated ...
McAuley, Daniel F, Orme, RML, Singer, M, L'E Orme, Robert M, Alexina J Mason, McAuley DF, Mason, Alexina J., Orme, Robert M L'E, Ashby D, Orme, Robert M., Mason, Alexina J, Liu, KD, Perkins, Gavin D., McAuley, Daniel F.; id_orcid, Gordon, Anthony C., Robert M Orme, Daniel F McAuley, Mason, AJ, Gordon, Anthony C, Gordon AC, Liu, Kathleen D., Orme RM, Gordon, AC, Mervyn Singer, Perkins, GD, Kathleen D Liu, Mason AJ, McAuley, Daniel F., Liu KD, Andrea Morelli, Ashby, D, Liu, Kathleen, Liu, Kathleen D, Gavin D Perkins, Morelli, A, Singer, Mervyn, Singer M, Perkins, Gavin D, Ashby, Deborah, Anthony C Gordon, Deborah Ashby, Orme, Robert MLE, Morelli, Andrea, Perkins GD, McAuley, DF   +44 more
core   +1 more source

Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial. [PDF]

, 2012
BACKGROUND: The purpose of this research is to develop and evaluate methods for conducting pragmatic cluster randomized trials in a primary care electronic database.
Wolfe Charles, Van Staa, Tjeerd; id_orcid, van Staa, Tjeerd, Mcdermott Lisa, Judith Charlton, Gulliford, Martin, Gerard McCann, Charlton, Judith, Ashworth Mark, Ashworth, Mark, Dregan Alex, McCann, Gerard, Charlton Judith, Anthony Rudd, Rudd Anthony, Lucy Yardley, Mark Ashworth, Gulliford Martin, Dregan, Alex; id_orcid, McCann Gerard, Lisa Mcdermott, Martin Gulliford, Tjeerd van Staa, Dregan, Alex, Yardley, Lucy, ?, ?, McDermott, Lisa, van Staa Tjeerd, null null, Wolfe, Charles, Yardley Lucy, Rudd, Anthony, eCRT Research Team, Charles Wolfe, Alex Dregan   +34 more
core   +2 more sources

Effect of head and facial massage combined with aromatherapy on sleep quality and delirium in patients with acute myocardial infarction: A randomized controlled trial

Complementary Therapies in Medicine
Background: Delirium and sleep disturbances are common among patients with acute myocardial infarction (AMI) admitted to the Cardiac Intensive Care Unit (CCU), often leading to increased mortality and prolonged hospitalization.
Mehrnaz Kharatha, Somayeh Rezaie, Seyedeh Solmaz Talebi, Hossein Ebrahimi   +3 more
doaj   +1 more source

Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D3 and/or calcium (RECORD Trial) [PDF]

, 2012
Context: Vitamin D or calcium supplementation may have effects on vascular disease and cancer. Objective: Our objective was to investigate whether vitamin D or calcium supplementation affects mortality, vascular disease, and cancer in older people ...
McDonald, AM, Campbell, MK, Torgerson, DJ, Marsh, D., RECORD Trial Group, Pant, Puspa R., Grant, Adrian, Adrian M. Grant, Wallace, W Angus., Wallace, W. Angus, Eastell, R., Campbell, Marion K., Robinson, C. Michael, Cyrus Cooper, David J. Torgerson, Maclennan, Graeme S., Wallace, WA, McPherson, GC, Avenell, A, null null, Grant, AM, Francis, Roger M., Graeme S. MacLennan, William J. Gillespie, Jenkinson, David, Khaw, K. T., Francis, RM, McDonald, GM, Pant, PR, C. Michael Robinson, Cooper, Cyrus, Alison M. McDonald, Roger M. Francis, McDonald, Alison M., Jenkinson, David J., Frazer H. Anderson, W. Angus Wallace, Torgerson, David J., David J. Jenkinson, Robinson, CM, Puspa R. Pant, Grant, Adrian M., Anderson, FH, Marion K. Campbell, Pant, Puspa Raj, Anderson, Frazer H., Alison Avenell, Cooper, C, Avenell, Alison, McPherson, Gladys C., Gillespie, William J., Gladys C. McPherson, Gillespie, WJ, Maclennan, GS   +53 more
core   +1 more source

Intraoperative and postoperative clinical evaluation of the hysteroscopic morcellator system for endometrial polypectomy: A prospective, randomized, single-blind, parallel group comparison study

Gynecology and Minimally Invasive Therapy, 2018
Objective: To evaluate the TRUCLEAR™ system (Smith and Nephew Inc., London, UK), a hysteroscopic system that morcellates and aspirates masses, in terms of the operating time, surgeon's convenience, and effect on patients compared with conventional ...
Akira Tsuchiya, Yasunori Komatsu, Reiko Matsuyama, Hiroko Tsuchiya, Yuri Takemura, Osamu Nishii   +5 more
doaj   +1 more source

Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia

JCSM Rapid Communications, 2022
Background Cancer cachexia (CC) impacts quality of life, physical function, anticancer treatment response, and survival. Inflammation is a prominent pathomechanism of CC.
David Blum, Caroline Hertler, Rolf Oberholzer, Susanne deWolf‐Linder, Markus Joerger, Christoph Driessen, Florian Strasser   +6 more
doaj   +1 more source

Systematic techniques for assisting recruitment to trials (START): study protocol for embedded, randomized controlled trials [PDF]

, 2014
Background Randomized controlled trials play a central role in evidence-based practice, but recruitment of participants, and retention of them once in the trial, is challenging.
Anne Kennedy, Shaun Treweek, Madurasinghe, Vichithranie, Wallace, P, David J. Collier, Paul Wallace, Kennedy, A, Bower, P; id_orcid, Peter Knapp, Treweek, S, Small, N; id_orcid, Bower, P, Eldridge, Sandra, Graffy, Jonathan, Graffy, J, David Torgerson, Wallace, Paul, Knapp, P, Nicola Small, Hughes-Morley, A, Salisbury, Chris, Treweek, Shaun, Eldridge, S, Chris Salisbury, Small, N, Torgerson, D, Peter Bower, Bower, Peter, Hughes-Morley, Adwoa, Madurasinghe, V, Knapp, Peter, Torgerson, David, Rick, J, Adwoa Hughes-Morley, Rick, Jo, Salisbury, C, Kennedy, Anne, Collier, DJ, Jonathan Graffy, Vichithranie Madurasinghe, Jo Rick, Collier, David J, Small, Nicola, Sandra Eldridge   +43 more
core   +2 more sources