Results 41 to 50 of about 4,658,408 (267)

Alcohol Screening and Brief Interventions for Offenders in the Probation Setting (SIPS Trial): a Pragmatic Multicentre Cluster Randomized Controlled Trial [PDF]

, 2014
Aim - To evaluate the effectiveness of different brief intervention strategies at reducing hazardous or harmful drinking in the probation setting. Offender managers were randomized to three interventions, each of which built on the previous one: feedback
Patton, Robert, Myles, J., Dale, V, Drummond, Colin, Shepherd, Jonathan, Perryman, K, Parrott, S, Phillips, T, Newbury-Birch, Dorothy; id_orcid, Drummond, Colin; id_orcid, Newbury-Birch, Dorothy, Dale, Veronica, Myles, J, Cassidy, P., Phillips, T., Cassidy, Paul, Cassidy, P, Godfrey, Christine, Deluca, Paolo; id_orcid, Gilvarry, Eilish, Myles, Judy, Kaner, Eileen, Kaner, E, Oyefeso, A, Newbury-Birch, D, Patton, R, McGovern, Ruth, McGovern, R, Bland, Martin, Perryman, Katherine, Phillips, Tom, Shepherd, J, Gilvarry, E, Deluca, P, Godfrey, C, Drummond, C, Heather, Nick, Bland, M, Oyefeso, Adenekan, Heather, N, Coulton, Simon, Deluca, Paolo, Parrott, Steve, Coulton, S   +43 more
core   +1 more source

Comparing the Effects of Hot Shower and Intravenous Injection of Hyoscine on the Pain Intensity and Duration of Active Phase of Labour in Nulliparous Women [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Parturition is a painful process and one of midwives’ duties is to reduce the pain during labour. Aim: To compare the effect of hot shower and intravenous injection of hyoscine on the pain severity and duration of active phase of labour ...
Safa Maddady Maddady, Sakineh Mohammad-Alizadeh-Charandabi, Fahimeh Sehhatti Shafaei, Mojgan Mirghafourvand   +3 more
doaj   +1 more source

Electroacupuncture Treatment for Women with Primary Obesity: A Review of Randomized Controlled Trials [PDF]

Journal of Acupuncture Research, 2020
The purpose of this review was to evaluate the effectiveness of electroacupuncture treatment for women with “primary obesity.” Primary obesity is caused by an imbalance in energy intake and consumption due to abnormal eating and living habits in the ...
Soo Jin Lee, Da Yoon Oh, Jae Eun Park, Min Cheol Lee, Myung Kyu Jeon, Yeong Suk Jang, Hyeon Jin Kim, Jae Young Ahn, Noo ri Hong, Woo Young Kim   +9 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Registry or randomization – must it be evidence or could it be coincidence?

Innovative Surgical Sciences
Over the years, clinical registries and randomized controlled trials gained acceptance. With increasing experience, it was possible to obtain knowledge of benefits and limitations in both designs.
Radulova Olga, Oehme Florian, Korn Sandra, Praetorius Christian, Distler Marius, Weitz Jürgen   +5 more
doaj   +1 more source

Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial

Hypertension in Pregnancy, 2017
Objective: To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension.
Kathryn J. Sharma, Naomi Greene, Sarah J. Kilpatrick   +2 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression [PDF]

, 2012
Background: Randomized, double-blind, placebo-controlled trials constitute the gold standard in clinical research when testing the efficacy of new psychopharmacological interventions in the treatment of major depression.
Berger Michael, Dittmann, Sandra, Riedel Michael, Sophia, Frangou, Emanuel Severus, Bauer Michael, Severus, Emanuel, Pfennig Andrea, Florian Seemüller, Sophia Frangou, Michael, Bauer, Michael Bauer, Michael Riedel, Berger, Michael, Michael, Obermeier, Andrea, Pfennig, Michael Obermeier, Obermeier Michael, Seemüller Florian, Andrea Pfennig, Michael Berger, Hans-Jürgen, Möller, Dittmann Sandra, Michael, Riedel, Severus Emanuel, Frangou Sophia, Seemüller, Florian, Möller Hans-Jürgen, Sandra Dittmann, Hans-Jürgen Möller   +29 more
core   +2 more sources

Evaluating the Feasibility of Using Historical Placebo Control in Osteoarthritis Trials

Epidemiologia
Background/Objectives: Randomized controlled trials (RCTs) are the gold standard for evaluating treatment efficacy, yet recruitment and retention remain challenging, particularly when placebo arms are required.
Justine Monseur, Emma Barbeau, Anne-Françoise Donneau, Olivier Bruyère   +3 more
doaj   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source