Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial. [PDF]
BACKGROUND: The purpose of this research is to develop and evaluate methods for conducting pragmatic cluster randomized trials in a primary care electronic database.
Wolfe Charles +34 more
core +2 more sources
Low Dose Celecoxib Combined with Clozapine for Treatment of Schizophrenia: A Double Blind Randomized Clinical Trial [PDF]
Introduction: Higher levels of pro-inflammatory cytokines in schizophrenia have suggested that dysfunctions of the immune system may play a role in this disabling condition.
Roya Samadi +4 more
doaj +1 more source
Alcohol Screening and Brief Interventions for Offenders in the Probation Setting (SIPS Trial): a Pragmatic Multicentre Cluster Randomized Controlled Trial [PDF]
Aim - To evaluate the effectiveness of different brief intervention strategies at reducing hazardous or harmful drinking in the probation setting. Offender managers were randomized to three interventions, each of which built on the previous one: feedback
Patton, Robert +43 more
core +1 more source
Promoting Independence in Dementia (PRIDE): A Feasibility Randomized Controlled Trial
Emese Csipke,1 Aisha Shafayat,2 Kirsty Sprange,2 Lucy Bradshaw,2 Alan A Montgomery,2 Reuben Ogollah,2 Esme Moniz-Cook,3 Martin Orrell4 1Division of Psychiatry, University College London, London, UK; 2Nottingham Clinical Trials Unit, University of ...
Csipke E +7 more
doaj
Each guideline recommendation from the American Heart Association and the American College of Cardiology includes an indication of the level of supporting evidence and the associated strength of recommendation with “IA” recommendations representing those
Emily P. Zeitler +4 more
doaj +1 more source
Evaluation of Randomized Controlled Trials [PDF]
Although randomized controlled trials (RCTs) play a key role in modern medicine, considerable variability exists in their quality and in the reliability (reproducibility) of their results. The present article discusses features that characterize high-quality trials, such as intent-to-treat (ITT) analysis, the avoidance of patient exclusions, and a ...
openaire +2 more sources
Effects of study design and allocation on participant behaviour-ESDA: study protocol for a randomized controlled trial [PDF]
Background: What study participants think about the nature of a study has been hypothesised to affect subsequent behaviour and to potentially bias study findings.
Kypri, Kypros +27 more
core +2 more sources
Background Gastroscopy procedures are frequently performed under general sedation to minimize discomfort. Patients who refuse a sedative injection may experience more discomfort and adverse reactions such as pain and nausea.
Binyu Yu +7 more
doaj +1 more source
Weight management for overweight and obese men delivered through professional football clubs: a pilot randomized trial [PDF]
Background: The prevalence of male obesity is increasing, but men are less likely than women to attend existing weight management programmes. We have taken a novel approach to reducing perceived barriers to weight loss for men by using professional ...
Shaun Treweek +20 more
core +2 more sources
Electroacupuncture treatment for sarcopenia: study protocol for a randomized controlled trial
Introduction Sarcopenia is a disease primarily characterized by age-related loss of skeletal muscle mass, muscle strength, and/or decline in physical performance.
Hao Li +11 more
doaj +1 more source

