Results 71 to 80 of about 4,272,652 (308)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
مراقبت پرستاری و مامایی ابن سینا, 2018 Introduction: Anxiety is one of the prevalent events before and after surgery which occurs in patients due to the waiting time for heart surgery, hospitalization, fear of death, and in general the fear of unknowns. This study was conducted to investigate
Kosar Fahimi +5 more
doaj
Trials, 2018 Background Poststroke depression is closely related to increased mortality in stroke patients. Compared with antidepressants, electroacupuncture (EA) treatment for poststroke depression (PSD) has relatively more stable effectiveness and can reduce side ...
Wa Cai +3 more
doaj +1 more source
Effects of In-Bed Cycle Exercise in Patients With Acute Stroke: A Randomized Controlled Trial
Archives of Rehabilitation Research and Clinical Translation, 2020 Objective: To investigate the effects of in-bed cycle exercise in addition to usual care in patients with acute stroke, National Institutes of Health Stroke Scale (NIHSS) 7-42, regarding walking ability, functional outcomes, and inpatient care days ...
Klas Sandberg, MSc, RPT +3 more
doaj +1 more source
Web-based physiotherapy for people affected by multiple sclerosis: a single blind, randomized controlled feasibility study [PDF]
, 2018 Objective: To examine the feasibility of a trial to evaluate web-based physiotherapy compared to a standard home exercise programme in people with multiple sclerosis. Design: Multi-centre, randomized controlled, feasibility study.
Alex McConnachie +16 more
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Effects of Vitamin D on Sexual Function and Hormones in Women with Multiple Sclerosis [PDF]
Journal of Client-centered Nursing CareBackground: Sexual dysfunction (SD) is the most common and challenging complication among women with multiple sclerosis (MS). Despite investigations into the impact of taking vitamin D on sexual function (SF), findings have not definitively recommended ...
Simin Zarabadi-pour +5 more
doaj
WISDOM: history and early demise - was it inevitable?
, 2007 In 1989, the UK Medical Research Council (MRC) agreed that, if feasible, a randomized controlled trial to assess the long-term risks and benefits of hormone replacement therapy (HRT) was a priority.
Darbyshire, J, Meade, T, Vickers, M
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source