Results 91 to 100 of about 4,375,535 (213)

Estimating vaccine efficacy during open-label follow-up of COVID-19 vaccine trials based on population-level surveillance data

Epidemics
While rapid development and roll out of COVID-19 vaccines is necessary in a pandemic, the process limits the ability of clinical trials to assess longer-term vaccine efficacy. We leveraged COVID-19 surveillance data in the U.S.
Mia Moore, Yifan Zhu, Ian Hirsch, Tom White, Robert C. Reiner, Ryan M. Barber, David Pigott, James K. Collins, Serena Santoni, Magdalena E. Sobieszczyk, Holly Janes   +10 more
doaj   +1 more source

Pain relief in dysmenorrhea: Exploring hypnosis as an alternative therapy

CHRISMED Journal of Health and Research, 2016
Objective: Dysmenorrhea is a widespread medical problem among young females. Hypnosis has been successfully tried for alleviation of different types of pain. In this randomized control trial, we compared it with nonsteroidal anti-inflammatory drug (NSAID)
Maitri Shah, Anuradha Monga, Sangita V Patel, Malay Shah, Harsh Bakshi   +4 more
doaj   +1 more source

Human Recognition among HIV-Infected Adults: Empirical Evidence from a Randomized Controlled Trial in Kenya [PDF]

This paper uses data from a randomized controlled trial to study the impacts of food supplementation and medical treatment on the receipt of human recognition by malnourished, HIV-infected adults in Kenya.
Tony Castleman
core  

How necessary are randomized controlled trials? [PDF]

, 2012
Randomized controlled trials (RCTs) are often deemed the gold standard for testing new treatments. This belief in turn justifies recruiting patients into such trials even when it is suspected that a new treatment is superior – although patients in the ...
Northcott, Robert
core   +3 more sources

Revisiting the Randomized Controlled Trial

Pakistan Journal of Medical Sciences, 2017
doi: https://doi.org/10.12669/pjms.333.13221How to cite this:Zulfiqar H. Revisiting the Randomized Controlled Trial. Pak J Med Sci. 2017;33(3):517-518.   doi: https://doi.org/10.12669/pjms.333.13221This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which ...
openaire   +2 more sources

Randomized controlled trial of a smartphone app designed to reduce unhealthy alcohol consumption

Internet Interventions
Background and aims: Unhealthy alcohol use is common and causes tremendous harm. Most people with unhealthy alcohol use will never seek formal alcohol treatment.
John A. Cunningham, Alexandra Godinho, Christina Schell, Joseph Studer, Jeffrey D. Wardell, Claire Garnett, Nicolas Bertholet   +6 more
doaj   +1 more source

Vitamin D with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials. [PDF]

, 2012
Introduction: Vitamin D may affect multiple health outcomes. If so, an effect on mortality is to be expected. Using pooled data from randomized controlled trials, we performed individual patient data (IPD) and trial level meta-analyses to assess ...
Salovaara, K., Smith, H.E., Jackson, Rebecca D, Sanders, Kerrie M., Jacobs, ET, Rebecca D Jackson (16135031), Sanders, KM, Tahir Masud (804313), Jacobs, E.T., JoAnn E Manson (13567339), Robbins, John A., Salovaara, K, Haakon E Meyer (10282121), Rejnmark, Lars, Abrahamsen, Bo, Jackson, Rebecca D., Mosekilde, Leif, Brixen, K., Mosekilde, L., Robbins, JA, Cyrus Cooper (141250), Lars Rejnmark (3752971), Mosekilde, L, Elizabeth T Jacobs (16135028), Bo Abrahamsen (650396), Meyer, Haakon E., Jackson, RD, Alison Avenell (82040), Jacobs, Elizabeth T., Smith, Helen E, Abrahamsen, Bo; id_orcid, Brixen, K, Salovaara, Kari, Manson, Joann E, Torgerson, D., Robbins, J.A., Avenell, A, Robbins, John A, Francis, Roger M., Roger M Francis (7380278), Abrahamsen, B, Masud, T, Jacobs, Elizabeth T, Manson, JoAnn E., Anderson, F., Francis, R.M., Kerrie M Sanders (13488952), Francis, RM, David Torgerson (462403), Masud, T., Helen E Smith (16045475), Abrahamsen, B., Manson, J.E., Cooper, Cyrus, Sanders, K.M., Frazer Anderson (16135022), Meyer, Haakon E, Anderson, F, Torgerson, D, Kari Salovaara (16135025), Meyer, H.E., Rejnmark, L, Francis, Roger M, John A Robbins (8553495), Torgerson, David, Masud, Tahir, Smith, HE, Anderson, Frazer, Cooper, C., Meyer, HE, Kim Brixen (16135034), Jackson, R.D., Smith, Helen E., Cooper, C, Rejnmark, L., Manson, JE, Avenell, Alison, Avenell, A., Brixen, Kim, Leif Mosekilde (349340), Sanders, Kerrie M   +80 more
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Randomized controlled trial of Micro-Mobile Compression® on lactate clearance and subsequent exercise performance in elite male cyclists

Open Access Journal of Sports Medicine, 2013
Iñigo San Millán,1 Kristen Bing,1 Carrie Brill,1 John C Hill,1 Larry E Miller2 1University of Colorado School of Medicine, Aurora, CO, 2Miller Scientific Consulting, Inc, Arden, NC, USA Background: The purpose of this paper was to assess ...
San Millán I, Bing K, Brill C, Hill JC, Miller LE   +4 more
doaj  

Selective Trials: A Principal-Agent Approach to Randomized Controlled Experiments [PDF]

We study the design of randomized controlled experiments in environments where outcomes are significantly affected by unobserved effort decisions taken by the subjects(agents). While standard randomized controlled trials (RCTs) are internally consistent,
Erik Snowberg, Gerard Padro i Miquel, Sylvain Chassang   +2 more
core  

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI) [PDF]

, 2014
AimDespite prompt revascularization of acute myocardial infarction (AMI), substantial myocardial injury may occur, in part a consequence of ischaemia reperfusion injury (IRI). There has been considerable interest in therapies that may reduce IRI.
Singh, Satnam, Lim, Pitt O, Christopher Neil (433186), Bruce, M, Broadhurst, Paul, Madhani, Melanie; id_orcid, Nishat Siddiqi (7733786), Schwarz, Konstantin, Awsan, Noman, Jansen, Else, McPherson, Gladys, Dawson, Dana, Slattery, Elaine, Struthers, Allan, McDonald, Alison, Rhodes, Jonathan, Neil, Christopher, Toff, William, Bruce, M., Garg, Deepak, Siddiqi, N, Firoozi, Sami, Kaski, JC, Madhani, M., Nicholas Boon (7733804), Kaski, Juan-Carlo, Sofia Papadopoulou (7733789), Horowitz, J, Bennett, Lorraine, Horowitz, J., Frenneaux, Michael, Boon, N., Bruce, Margaret, Hildick-Smith, David, Lim, P., Neil, C., Nightingale, Peter, Pitt O. Lim (7733795), Graeme MacLennan (275485), Hannah, Andrew, Feelisch, M., Melanie Madhani (3851305), Roberts, Elved, Dawson, D, David Hildick-Smith (7733798), Madhani, M, Kaski, Juan Carlos, Lim, PO, Stewart, Andrew, Cooter, Nina, Rajendran, Sharmalar, Horowitz, John, Lang, Chim, Papadopoulou, Sofia A., NIAMI investigators, Jagpal, Baljit, Cotton, S, Siddiqi, N., Gonzalvez, Fatima, Feelisch, Martin, Madhani, Melanie, Boon, Nicholas, Nicholas Bunce (7733792), Brown, Sue, Roy, David, Bunce, N., Bunce, N, Papadopoulou, S, Dawson, D., Frenneaux, M., Michael Frenneaux (3576296), Davidson, Tracey, Siddiqi, Nishat, Dargie, Henry, Feelisch, M, Neil, C, Dana Dawson (7020656), Hildick-Smith, D., Frenneaux, M, Hildick-Smith, D, Bunce, Nicholas, NIAMI investigators (7733810), Cotton, Seonaidh, Seonaidh Cotton (503485), de Belder, Adam, Papadopoulou, S., Black, Marilyn, Kaski, J., Hogg, Duncan, Dautov, Rustem, Metcalfe, Malcolm, Bogle, Richard, Cotton, S., Boon, N, Martin Feelisch (358503), John Horowitz (7733801), Margaret Bruce (782483), Lim, Pitt O., MacLennan, G, Cotton, Seonaidh Claire, Juan Carlos Kaski (7733807), Maclennan, Graeme, Papadopoulou, Sofia, MacLennan, G.   +103 more
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