Results 61 to 70 of about 4,658,408 (267)

The importance of clinical trial protocols

HSJ
The International Committee of Medical Journal Editors (ICMJE) and the World Health Organization (WHO) define a clinical trial as any research that prospectively assigns participants or groups of human subjects to one or more interventions (medicines ...
Melissa Andreia de Moraes Silva
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Aromatherapy Massage for Breast Cancer Patients: A Randomized Controlled Trial [PDF]

, 2018
The aim of this large randomized controlled study was to test the value of Aromatherapy (AM) with breast cancer patients for reducing symptoms, such as pain, anxiety, depression, emotional responses, insomnia, nausea/vomiting and the ability to cope ...
Anne Clemo-Crosby, Jenny Day Claire Stidston Shannon McGinley Roy John Powell
core   +1 more source

Investigation of the Effect of Multimedia Education on Anxiety Before and After Surgery in Patients Undergoing Coronary Artery Bypass Graft Surgery

مراقبت پرستاری و مامایی ابن سینا, 2018
Introduction: Anxiety is one of the prevalent events before and after surgery which occurs in patients due to the waiting time for heart surgery, hospitalization, fear of death, and in general the fear of unknowns. This study was conducted to investigate
Kosar Fahimi, Ali Abbasi, Mahdi Zahedi, Farzaneh Amanpour, Maryam Gilani, Hossein Ebrahimi   +5 more
doaj  

Effect of high-definition transcranial direct current stimulation among late-subacute and chronic stroke survivors with fatigue: A randomized-controlled crossover trial protocol

MethodsX
Post-stroke fatigue (PSF) is a commonly overlooked symptom that impacts daily functioning and quality of life. It is caused by altered functional connectivity within the brain networks, which can potentially be influenced by neuromodulation.
Akhila Jagadish, Manikandan Natarajan, Divya Bharatkumar Adhia, Annapoorna Kuppuswamy, Vasudeva Guddattu, John M. Solomon   +5 more
doaj   +1 more source

Efficacy and safety of electroacupuncture for post stroke depression: study protocol for a randomized controlled trial

Trials, 2018
Background Poststroke depression is closely related to increased mortality in stroke patients. Compared with antidepressants, electroacupuncture (EA) treatment for poststroke depression (PSD) has relatively more stable effectiveness and can reduce side ...
Wa Cai, Wen Ma, Guan-Tao Wang, Wei-Dong Shen   +3 more
doaj   +1 more source

A randomized controlled trial on the effect of focal thermal therapy at acupressure points treating osteoarthritis of the knee

Journal of Orthopaedic Surgery and Research, 2021
Background Osteoarthritis of the knee is a common degenerative joint disorder in our ageing population. A combination of thermal therapy with a self-management exercise have shown a positive effect in the management of osteoarthritis of the knee.
Kevin Ki-Wai Ho, Anthony Wai-Leung Kwok, Wai-Wang Chau, S. M. Xia, Y. L. Wang, Jack Chun-Yiu Cheng   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Weight management for overweight and obese men delivered through professional football clubs: a pilot randomized trial [PDF]

, 2013
Background: The prevalence of male obesity is increasing, but men are less likely than women to attend existing weight management programmes. We have taken a novel approach to reducing perceived barriers to weight loss for men by using professional ...
Shaun Treweek, Gray, Cindy M., Mutrie, N., Cindy M Gray, Gray, C.M., Hunt, Kate, Anderson, Annie S., Hunt, K., Mutrie, Nanette, Sally Wyke, Gray, Cindy M, Annie S Anderson, Wyke, Sally, Wyke, S., Treweek, S., Anderson, Annie S, Nanette Mutrie, Anderson, Annie S.; id_orcid, Kate Hunt, Treweek, Shaun, Anderson, A.S.   +20 more
core   +1 more source

The Effects of Vitamin D on Sexual Function and Hormones in Women with Multiple Sclerosis [PDF]

Journal of Client-centered Nursing Care
Background: Sexual dysfunction (SD) is the most common and challenging complication among women with multiple sclerosis (MS). Despite investigations into the impact of taking vitamin D on sexual function (SF), findings have not definitively recommended ...
Simin Zarabadi-pour, Mohammad Eghbali, Leila Amini, Seyed Massood Nabavi, Hamid Haghani, Homa Sadeghi Avval Shahr   +5 more
doaj