Results 201 to 210 of about 2,170,785 (365)

A European multicenter randomized controlled trial of single dose surfactant therapy for idiopathic respiratory distress syndrome [PDF]

, 1990
Jeffrey D. Horbar, Roger F. Soll, Hartmut Schächinger, G Kewitz, Hans Versmold, Wolfgang Lindner, G. Duc, D Mieth, O Linderkamp, E. P. Zilow, P. Lemburg, V von Loewenich, Marek Brand, I Minoli, Guido E. Moro, K Riegel, R. Roos, Laurence Weiss, Jerold F. Lucey   +18 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia [PDF]

, 1993
DC Dale, MA Bonilla, MW Davis, AM Nakanishi, WP Hammond, Joanne Kurtzberg, W Wang, Ann A. Jakubowski, Emma De Winton, Parviz Lalezari   +9 more
openalex   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Treatment-control comparisons in platform trials including non-concurrent controls [PDF]

arXiv
Shared controls in platform trials comprise concurrent and non-concurrent controls. For a given experimental arm, non-concurrent controls refer to data from patients allocated to the control arm before the arm enters the trial. The use of non-concurrent controls in the analysis is attractive because it may increase the trial's power of testing ...
arxiv  

Steroid treatment of acute alcoholic hepatitis. Analysis of the seven randomized control trials

, 1978
Eli Kirschner, Barry Silverman, Brian G. Blackburn   +2 more
openalex   +1 more source

Per-rectal pulsed irrigation versus per-oral colonic lavage for colonoscopy preparation: a randomized, controlled trial [PDF]

, 1991
Kenneth J. Chang, Richard A. Erickson, Steven L. Schandler, Tom Coye, Chris Moody   +4 more
openalex   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

The Use of Web-Based Support Groups Versus Usual Quit-Smoking Care for Men and Women Aged 21-59 Years: Protocol for a Randomized Controlled Trial (Preprint) [PDF]

, 2019
BACKGROUND Existing smoking cessation treatments are challenged by low engagement and high relapse rates, suggesting the need for more innovative, accessible, and interactive treatment strategies.
Calder, Douglas, Delucchi, Kevin, Pechmann, Cornelia Ann, Phillips, Connor, Prochaska, Judith J   +4 more
core  

Effects of repeated intra-silicone oil injections of methotrexate on proliferative vitreoretinopathy grade C: a multicenter randomized controlled trial

Scientific Reports
In this randomized controlled trial, we assessed the effects of three consecutive intra-silicone oil (SO) injections of methotrexate (MTX) on the outcomes of surgery for proliferative vitreoretinopathy grade C (PVR-C).
Ramin Nourinia, Sare Safi, Mehrad Mohammadpour, Hamid Riazi-Esfahani, Mohammad Reza Ansari Astaneh, Khalil Ghasemi Falavarjani, Alireza Ramezani, Saeed Karimi, Sahba Fekri, Nazanin Ebrahimiadib, Elias Khalili Pour, Homayoun Nikkhah, Nasser Shoeibi, Narges Hassanpoor, Maryam Hosseini, Mojtaba Abrishami, Fatemeh Abdi, Anoushiravan Rahimi, Mohammad Hossein Jabbarpoor Bonyadi, Siamak Moradian, Sina Khosravi Mirzaei, Hamid Safi, Pasha Anvari, Kaveh Fadakar, Masoud Mirghorbani, Niloufar Mohammadbagheri, Firouze Hatami, Bahareh Kheiri, Mehdi Yaseri, Zahra Khorrami, Hamid Ahmadieh   +30 more
doaj   +1 more source