Results 131 to 140 of about 1,439,746 (305)

The Effect of Randomized Beta-Carotene Supplementation on CKD in Men

open access: yesKidney International Reports
Introduction: Beta-carotene (BC) protects the body against free radicals that may damage the kidney and lead to the development of acute kidney injury and chronic kidney disease (CKD).
Api Chewcharat   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Components of effective randomized controlled trials of hydrotherapy programs for fibromyalgia syndrome: A systematic review

open access: yesJournal of Pain Research, 2009
Luke Perraton, Zuzana Machotka, Saravana KumarInternational Centre for Allied Health Evidence, University of South Australia, Adelaide, South Australia, AustraliaAim: Previous systematic reviews have found hydrotherapy to be an effective management ...
Luke Perraton   +2 more
doaj  

Do ACE inhibitors prevent nephropathy in type 2 diabetes without proteinuria? [PDF]

open access: yes, 2004
Angiotensin-converting enzyme (ACE) inhibitors make a significant difference for patients with diabetes as a whole. If patients both with and without microalbuminuria are included together, ACE inhibitors significantly reduce the progression of the ...
Dodson, Sherry   +2 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Cluster Randomized Controlled Trials (CRCTs) in Evidence-Based Dentistry

open access: yesDental Hypotheses, 2012
A cluster randomized controlled trial (CRCT) is a type of randomized controlled trial in which groups of subjects (as opposed to individual subjects) are randomized.
Francesco Chiappelli
doaj  

Randomized, Controlled Trials

open access: yesAnnals of Surgery, 2006
During the 1960s and 1970s, the first randomized controlled trials in surgery were performed. Prior to this, surgical advances were largely made by physiologic experimentation in the laboratory and careful observation of series of patients. By relying on these types of studies, there was no doubt that appendectomy for acute appendicitis, surgery for ...
openaire   +2 more sources

When do Words Matter? Understanding the Impact of Lexical Choice on Audience Perception using Individual Treatment Effect Estimation

open access: yes, 2018
Studies across many disciplines have shown that lexical choice can affect audience perception. For example, how users describe themselves in a social media profile can affect their perceived socio-economic status.
Culotta, Aron, Wang, Zhao
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Does a Low-Sodium Diet Reduce Blood Pressure? [PDF]

open access: yes, 2004
Reducing sodium intake does lead to a slightly lower average blood pressure. However, no evidence from controlled trials proves that reducing sodium intake decreases morbidity or mortality, or proves that modest sodium restriction is harmful.
Smucny, John
core  

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