Results 291 to 300 of about 313,863 (333)

Topical cyclosporin in oral lichen planus: a controlled, randomized, prospective trial

British Journal of Dermatology, 2006
The published studies of topical cyclosporin (CyA) therapy in chronic oral lichen planus (OLP) have shown conflicting results. We report an investigator-blinded study of 13 patients with OLP, who were randomly assigned to treatment with CyA (500 mg as a swish-and-spit medication for 5 min three times daily) or a corticosteroid oral paste (triamcinolone
H. von Domarus, L Färber, Peter Sieg, V Von Zitzewitz, H Iven   +4 more
openaire   +2 more sources

Topical Anesthetics for Dermal Instrumentation: A Systematic Review of Randomized, Controlled Trials

Annals of Emergency Medicine, 2005
We compare the analgesic efficacy of topical anesthetics for dermal instrumentation with conventional infiltrated local anesthesia and also compare topically available amide and ester agents with a eutectic mixture of local anesthetics (EMLA).We conducted a systematic review of randomized, controlled trials.
Jocelyn M. Weiss, Daniel B. Carr, Anthony Eidelman, Joseph Lau   +3 more
openaire   +3 more sources

A randomized controlled trial of R-salbutamol for topical treatment of discoid lupus erythematosus

British Journal of Dermatology, 2009
In a recent open pilot trial, R-salbutamol sulphate, a well-known molecule with anti-inflammatory effects, was tested successfully on patients with therapy-resistant discoid lupus erythematosus (DLE).To compare the efficacy and safety of R-salbutamol cream 0.5% vs.
Jemec, G B E, Ullman, S, Goodfield, M, Bygum, A, Olesen, A B, Berth-Jones, J, Nyberg, F, Cramers, M, Faergemann, J, Andersen, P, Kuhn, A, Ruzicka, T   +11 more
openaire   +5 more sources

A Randomized Controlled Trial of Topical Cannabidiol for the Treatment of Thumb Basal Joint Arthritis

The Journal of Hand Surgery, 2022
Since the passage of the Agricultural Improvement Act of 2018, hand surgeons have increasingly encountered patients seeking counseling on over-the-counter, topical cannabidiol (CBD) for the treatment of pain. To this end, we designed a human clinical trial to investigate the therapeutic potential of CBD for the treatment of pain associated with thumb ...
John T, Heineman, Grace L, Forster, Kristen L, Stephens, Patrick S, Cottler, Michael P, Timko, Brent R, DeGeorge   +5 more
openaire   +2 more sources

Effects of Topical Antifibrinolytics in Endoscopic Sinus Surgery: A Pilot Randomized Controlled Trial

American Journal of Rhinology, 2007
Background Bleeding in endoscopic sinus surgery (ESS) may increase the risk of intraoperative complications and is associated with poorer outcomes Antifibrinolytic agents have been shown to reduce bleeding if administered systemically. The aim of this study was to determine the effect of topical epsilon-aminocaproic acid (EACA) and tranexamic acid (TA)
Achim G. Beule, Achim G. Beule, Peter J. Wormald, Theodore Athanasiadis   +3 more
openaire   +4 more sources

Topical Sucralfate Treatment of Anal Fistulotomy Wounds: A Randomized Placebo-Controlled Trial

Diseases of the Colon & Rectum, 2011
Sucralfate is a cytoprotective agent which adheres to mucoproteins and forms a protective barrier at wound sites. In oral form it is a common ulcer medication, and as a topical preparation it has been used to treat a wide variety of wounds.The present study was designed to evaluate the effectiveness and safety of topical sucralfate in wound healing ...
Surekha Kalaskar, Subhash A. Shrirao, Pravin J. Gupta, P. S. Heda   +3 more
openaire   +2 more sources

Effect of topical diclofenac on postoperative photorefractive keratectomy pain: a randomized, controlled trial

Clinical & Experimental Ophthalmology, 2014
AbstractBackgroundA major disadvantage of photorefractive keratectomy is postoperative pain and discomfort. This study aims to evaluate whether topical diclofenac 0.1% therapy adds any extra benefit to systemic diclofenac in controlling pain after photorefractive keratectomy.DesignProspective randomized, double‐masked clinical trial applied in the ...
Mojtaba Abrishami, Mojtaba Abrishami, Alireza Eslampoor, Asieh Ehsaei   +3 more
openaire   +3 more sources

Randomized Controlled Trial of Topical Hyperbaric Oxygen for Treatment of Diabetic Foot Ulcers

Diabetes Care, 1988
The effect of 2 wk of topical hyperbaric oxygen (THO) treatment on the healing of diabetic foot ulcers without associated gangrene was evaluated in a prospective, controlled, and randomized manner in 28 patients. There were 12 patients in the THO group (group 1) and 16 in the control group (group 2).
V J Ginunas, Rodney H Adkins, Camilo A Leslie, Francisco L. Sapico   +3 more
openaire   +2 more sources

Topical Anesthesia in Cutaneous Head and Neck Surgery: A Randomized Controlled Trial

Otolaryngology–Head and Neck Surgery
AbstractObjectiveCutaneous head and neck surgery can safely and effectively be performed using local anesthetic (LA). However, optimizing pain management during LA administration is paramount for patient comfort and procedural efficacy. The primary objective of this study was to investigate the comparative effectiveness of EMLA cream and ethyl chloride
Rory, O'Neill, Adrinda, Affendi, Nathaniel, McHugh, Liam, Skinner   +3 more
openaire   +2 more sources

Topical cyclosporine‐A versus prednisolone for herpetic stromal keratitis: a randomized controlled trial

Acta Ophthalmologica, 2018
AbstractPurposeTo compare topical cyclosporine‐A 2% eye drop (Cs‐A) with prednisolone acetate 1% eye drop for treatment of herpetic stromal keratitis (HSK).MethodsIn this randomized clinical trial, 38 eyes of 33 patients with HSK were randomly assigned to receive either 2% Cs‐A or 1% prednisolone acetate eye drops.
Mohamadreza Nayebzadeh, Alireza Peyman, Mohamadreza Peyman, Mohamadreza Peyman, Mohsen Pourazizi, Natalie A. Afshari   +5 more
openaire   +2 more sources