Results 291 to 300 of about 1,683,394 (322)
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Topical cyclosporin in oral lichen planus: a controlled, randomized, prospective trial

British Journal of Dermatology, 2006
The published studies of topical cyclosporin (CyA) therapy in chronic oral lichen planus (OLP) have shown conflicting results. We report an investigator-blinded study of 13 patients with OLP, who were randomly assigned to treatment with CyA (500 mg as a swish-and-spit medication for 5 min three times daily) or a corticosteroid oral paste (triamcinolone
H. von Domarus   +4 more
openaire   +2 more sources

Update on Randomized Placebo-Controlled Trials in the Past Decade for Treatment of Major Depressive Disorder in Child and Adolescent Patients: A Systematic Review.

Journal of child and adolescent psychopharmacology, 2018
OBJECTIVES Antidepressant treatment for major depressive disorder (MDD) has been a topic of continued interest with a number of placebo randomized-controlled trials (RCTs) being published in the past decade.
M. Ignaszewski, B. Waslick
semanticscholar   +1 more source

Topical Anesthetics for Dermal Instrumentation: A Systematic Review of Randomized, Controlled Trials

Annals of Emergency Medicine, 2005
We compare the analgesic efficacy of topical anesthetics for dermal instrumentation with conventional infiltrated local anesthesia and also compare topically available amide and ester agents with a eutectic mixture of local anesthetics (EMLA).We conducted a systematic review of randomized, controlled trials.
Jocelyn M. Weiss   +3 more
openaire   +3 more sources

Topical Tranexamic Acid in Breast Reconstruction: A Double-Blind, Randomized Controlled Trial

Plastic & Reconstructive Surgery, 2023
BACKGROUND Excess fluid accumulation (seroma/hematoma) around the breast implant post reconstruction can lead to significant complications. Topical administration of tranexamic acid (TXA) may reduce fluid accumulation and reduce post-operative complications.
Tyler, Safran   +4 more
openaire   +2 more sources

A randomized controlled trial of R-salbutamol for topical treatment of discoid lupus erythematosus

British Journal of Dermatology, 2009
In a recent open pilot trial, R-salbutamol sulphate, a well-known molecule with anti-inflammatory effects, was tested successfully on patients with therapy-resistant discoid lupus erythematosus (DLE).To compare the efficacy and safety of R-salbutamol cream 0.5% vs.
Jemec, G B E   +11 more
openaire   +5 more sources

A Randomized Controlled Trial of Topical Cannabidiol for the Treatment of Thumb Basal Joint Arthritis

The Journal of Hand Surgery, 2022
Since the passage of the Agricultural Improvement Act of 2018, hand surgeons have increasingly encountered patients seeking counseling on over-the-counter, topical cannabidiol (CBD) for the treatment of pain. To this end, we designed a human clinical trial to investigate the therapeutic potential of CBD for the treatment of pain associated with thumb ...
John T, Heineman   +5 more
openaire   +2 more sources

Effects of Topical Antifibrinolytics in Endoscopic Sinus Surgery: A Pilot Randomized Controlled Trial

American Journal of Rhinology, 2007
Background Bleeding in endoscopic sinus surgery (ESS) may increase the risk of intraoperative complications and is associated with poorer outcomes Antifibrinolytic agents have been shown to reduce bleeding if administered systemically. The aim of this study was to determine the effect of topical epsilon-aminocaproic acid (EACA) and tranexamic acid (TA)
Achim G. Beule   +3 more
openaire   +4 more sources

Topical Sucralfate Treatment of Anal Fistulotomy Wounds: A Randomized Placebo-Controlled Trial

Diseases of the Colon & Rectum, 2011
Sucralfate is a cytoprotective agent which adheres to mucoproteins and forms a protective barrier at wound sites. In oral form it is a common ulcer medication, and as a topical preparation it has been used to treat a wide variety of wounds.The present study was designed to evaluate the effectiveness and safety of topical sucralfate in wound healing ...
Surekha Kalaskar   +3 more
openaire   +2 more sources

Videogames and Health Improvement: A Literature Review of Randomized Controlled Trials.

Games for Health Journal, 2012
OBJECTIVE There are potential benefits of playing videogames for health improvement such as increasing knowledge about health-related issues by playing educational games and fighting a sedentary lifestyle by playing exergames.
Esmaeel Rahmani, S. Boren
semanticscholar   +1 more source

Effect of topical diclofenac on postoperative photorefractive keratectomy pain: a randomized, controlled trial

Clinical & Experimental Ophthalmology, 2014
AbstractBackgroundA major disadvantage of photorefractive keratectomy is postoperative pain and discomfort. This study aims to evaluate whether topical diclofenac 0.1% therapy adds any extra benefit to systemic diclofenac in controlling pain after photorefractive keratectomy.DesignProspective randomized, double‐masked clinical trial applied in the ...
Mojtaba Abrishami   +3 more
openaire   +3 more sources

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