Results 71 to 80 of about 666,640 (298)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Research in StatisticsWhen surveys involve sensitive issues-such as gambling habits, drug addiction, alcoholism, tax evasion, induced abortions, drunk driving, criminal history, or homosexuality non-response and response biases frequently occur, as respondents may be ...
Khalid Ul Islam Rather +2 more
doaj +1 more source
New Randomization Technique to Estimate the Population Mean of Quantitative Sensitive Variable [PDF]
International Journal of Mathematical, Engineering and Management SciencesSensitive topics such as workplace misconduct, corporate fraud, unethical decision-making, diversity and inclusion challenges, and leadership accountability often present significant obstacles in survey research.
Chandraketu Singh +2 more
doaj +1 more source
Extremal Mechanisms for Local Differential Privacy [PDF]
, 2015 Local differential privacy has recently surfaced as a strong measure of privacy in contexts where personal information remains private even from data analysts.
Kairouz, Peter +2 more
core
Efficient randomized-adaptive designs
, 2009 Response-adaptive randomization has recently attracted a lot of attention in the literature. In this paper, we propose a new and simple family of response-adaptive randomization procedures that attain the Cramer--Rao lower bounds on the allocation ...
He, Xuming, Hu, Feifang, Zhang, Li-Xin
core +1 more source
Treatment options for PNET liver metastases. a systematic review [PDF]
, 2018 Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo +8 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A novel randomized scrambling technique for mean estimation of a finite population
HeliyonIn recent decades, the randomized response technique has attracted researchers due to its usefulness in sensitive surveys. The randomized response procedure is used for the collection of responses on sensitive issues such as cheating in examination ...
Muhammad Azeem +5 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source