Results 71 to 80 of about 11,790,111 (286)

SCRAPPOR: An Efficient Privacy-Preserving Algorithm Base on Sparse Coding for Information-Centric IoT

IEEE Access, 2018
Different from the traditional Internet-of-Things (IoT) architecture, information-centric IoT is a novel paradigm in which changes are made to the entire network stack, from layer 3 up to the application layer.
Hui Cao, Shubo Liu, Longfei Wu, Zhitao Guan   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Bayesian Techniques in Randomized Response

Przegląd Statystyczny. Statistical Review, 2009
The issue of truthfulness of the answers given to socially or personally sensitive questions appeared at the very beginning of the construction of the surveys. The respondents often try to avoid answering a sensitive question or they do not tell the truth.
openaire   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Cheater detection for randomized response-techniques : derivation, analyses and application [PDF]

, 2017
Finding out how often an embarrassing characteristic exists in a population is accompanied by numerous problems that are due in particular to false answers as a consequence of social undesirability.
Feth, Sascha, Frenger, Monika, Pitsch, Werner, Schmelzeisen, Patrick   +3 more
core   +1 more source

Crafting an ingenious randomized response model for diverse questioning tactics

Franklin Open
When inquiries touch upon sensitive subjects like gambling habits, drug addiction, alcoholism, tendencies toward tax evasion, induced abortions, drunk driving, previous involvement in criminal activities, or matters related to sexuality in the context of
Manzoor A. Khanday, Tanveer A. Tarray, Dilawar A. Bhat   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

On the Bayesian Estimation of Synthesized Randomized Response Techniques for Obtaining Sensitive Information

International Journal of Mathematics and Mathematical Sciences
The reduction of response bias in survey research is crucial ensuring that the collected data accurately represents the target population. In this study, the Bayesian Estimation of the Synthesized Random Response Technique (BESRRT) estimators are ...
Olusegun S. Ewemooje, Isaac O. Adeniyi, Femi B. Adebola, Wilford B. Molefe   +3 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Using Randomized Response to Estimate the Proportion and Truthful Reporting Probability in a Dichotomous Finite Population

, 2009
In this paper, an alternative randomized response procedure is given that allows us to estimate the population proportion in addition to the probability of providing a truthful answer.
Chih-Li Wang, 張紘炬; Chang, Horng-jinh; Wang, Chin-li; Huang, Kuo-Chung, Kuo-Chung Huang, Horng-Jinh Chang   +3 more
core   +1 more source