Results 131 to 140 of about 1,465,496 (351)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Experimental evidence for variation across exclusive modifiers
GlossaThis paper is an investigation of variation across the English exclusive modifiers only, just, and merely—a domain that has received ample attention in the theoretical literature but has thus far not been subjected to experimental testing.
Eszter Ronai, Lucas Fagen
doaj +2 more sources
Statistical tests and estimators of the rank of a matrix and their applications in econometric modelling [PDF]
Testing and estimating the rank of a matrix of estimated parameters is key in a large variety of econometric modelling scenarios. This paper describes general methods to test for and estimate the rank of a matrix, and provides details on a variety of ...
Camba-Méndez, Gonzalo +1 more
core
Recovery of Low-Rank Plus Compressed Sparse Matrices with Application to Unveiling Traffic Anomalies
, 2012 Given the superposition of a low-rank matrix plus the product of a known fat compression matrix times a sparse matrix, the goal of this paper is to establish deterministic conditions under which exact recovery of the low-rank and sparse components ...
Giannakis, Georgios B. +2 more
core +1 more source
Qualitative Robustness of Rank Tests
The Annals of Statistics, 1982 An asymptotic notion of robust tests is studied which is based on the requirement of equicontinuous error probabilities. If the test statistics are consistent, their robustness in Hampel's sense and robustness of the associated tests turn out to be equivalent. Uniform extensions are considered. Moreover, test breakdown points are defined.
openaire +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
BMC Medical Research MethodologyBackground Pocock-Simon’s minimisation method has been widely used to balance treatment assignments across prognostic factors in randomised controlled trials (RCTs).
Ryusei Kimura +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A Class of Simple Distribution-free Rank-based Unit Root Tests (Revision of DP 2010-72) [PDF]
We propose a class of distribution-free rank-based tests for the null hypothesis of a unit root. This class is indexed by the choice of a reference density g, which needs not coincide with the unknown actual innovation density f.
Akker, R. van den +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source