Results 241 to 250 of about 1,471,856 (300)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Elevated somatostatin interneuron long-term potentiation minimally regulates temporoammonic plasticity in a mouse model of Fragile X Syndrome. [PDF]

Front Pharmacol
Wilson MA, Sumera A, Berk E, Booker SA.
europepmc   +1 more source

Decision-making in return to sport clearance after ACL reconstruction is primarily based on objective criteria: Insights from AGA knee experts. [PDF]

J Exp Orthop
Winkler PW, Achtnich AE, Schoepp C, Brandl G, Drenck TC, Glasbrenner J, Kittl C, Rauch G, Stein T, Drews BH, Willinger L.   +10 more
europepmc   +1 more source

Introducing the Event-Adjusted Rank Sum (EARS) Test: A Simple Approach to Survival Analysis Independent of Proportional Hazards. [PDF]

Biomed Res Int
Stålhammar G.
europepmc   +1 more source

Effect sizes for nonparametric tests. [PDF]

Biochem Med (Zagreb)
Fiel Peres F.
europepmc   +1 more source

Why your smartwatch may be misleading your doctor: a cross-sectional study on the impact of mobility aids on wearable accuracy in older adults. [PDF]

PeerJ
Özel A, Yakşi E, Çevik Ç, Nazar MR.
europepmc   +1 more source

Mathematical modeling of the cortisol stress response to develop indicators that are applicable across studies. [PDF]

Neurobiol Stress
de Nooij L, Posthuma JF, Miller R, Sep MSC, Quaedflieg C, Hernaus D, STRESS-EU Consortium, Vinkers CH, Hermans EJ.   +8 more
europepmc   +1 more source