Results 131 to 140 of about 12,421,662 (339)

Consistent ranking of multivariate volatility models [PDF]

open access: yes
A large number of parameterizations have been proposed to model conditional variance dynamics in a multivariate framework. This paper examines the ranking of multivariate volatility models in terms of their ability to forecast out-of-sample conditional ...
ROMBOUTS, Jeroen V.K.   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Piecewise-Defined Ranking Functions

open access: yes, 2013
International audienceWe present the design and implementation of an abstract domain for proving program termination by abstract interpretation. The domain automatically synthesizes piecewise-defined ranking functions and infers sufficient conditions for
Urban, Caterina
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Dominance relations when both quantity and quality matter, and applications to the\r\ncomparison of US research universities and worldwide top departments in economics [PDF]

open access: yes
In this article, we propose an extension of the concept of stochastic dominance intensively\r\nused in economics for the comparison of composite outcomes both the quality and the\r\nquantity of which do matter.
Agenor LAHATTE (OST)   +1 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Multidimensional Predictors of Ranking-Based Competitive Success in National-Level Junior Tennis Players: Evidence for the Dominant Role of Physical Performance

open access: yesSports
The aim of this study was to examine the relative contribution of physical performance, executive functions, and competitive anxiety to competitive success in junior tennis players.
Rita Géczi   +2 more
doaj   +1 more source

Discovering Ranking Functions for Information Retrieval

open access: yes, 2005
The field of information retrieval deals with finding relevant documents from a large document collection or the World Wide Web in response to a user’s query seeking relevant information.
Weiguo Fan, Praveen Pathak
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Ranking Investment Projects [PDF]

open access: yes
This paper describes conditions under which one investment project dominates a second project in terms of net present value, irrespective of the choice of the discount rate.
Foster, James E., Mitra, Tapan
core  

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