Results 151 to 160 of about 12,421,662 (339)
On the Impossibility of Certain Ranking
, 2007 Suppose all the individuals in a field are linearly ordered. Groups of individuals form teams. Is there a perfect ranking function of each team based on the members of the team?
Functions Jin-Yi Cai, Jin-yi Cai
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Analysis and Evaluation of Development of Urban Services Indicators in West Azerbaijan Province Cities by Using MCDM Techniques [PDF]
نشریه جغرافیا و برنامهریزی, 2015 The present paper, seeks to analyze and ranking the cities of west Azerbaijan province in terms of urban services development indicators with regard to the inseparable linkage between balanced distribution of urban facilities and services with social ...
Jamal Mohammadi +3 more
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Learning bivariate scoring functions for ranking
State-of-the-art Learning-to-Rank algorithms, e.g., λMART, rely on univariate scoring functions to score a list of items. Univariate scoring functions score each item independently, i.e., without considering the other available items in the list ...
Trani R., Nardini F. M., Venturini R.
core +1 more source
DBtrends: Publishing and benchmarking RDF ranking functions
, 2022 Providing accurate approaches for keyword search or question answering to access the data available on the Linked Data Web is of central importance to ensure that it can be used by non-experts.
Marx, Edgard +6 more
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