Results 91 to 100 of about 116,766 (290)

HyCell: Enabling GREEN Base Station Operations in Software-Defined Radio Access Networks

open access: yes, 2015
The radio access networks (RANs) need to support massive and diverse data traffic with limited spectrum and energy. To cope with this challenge, software-defined radio access network (SDRAN) architectures have been proposed to renovate the RANs. However,
Niu, Zhisheng   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Numerical Investigating the Effect of Water Depth on Ship Resistance Using RANS CFD Method

open access: yesPolish Maritime Research, 2019
On inland waterways the ship resistance and propulsive characteristics are strictly related to the depth of the waterway, thus it is important to have an understanding of the influence of water depth on ship hydrodynamic characteristics.
Hoa Nguyen Thi Ngoc   +4 more
doaj   +1 more source

SIGNIFICANCE OF M1 AND M2 POLARIZATION OF MONOCYTES-MACROPHAGES IN THE BLOOD FOR ATHEROSCLEROSIS RISK ASSESSMENT IN TYPE 2 DIABETES COMPARING WITH CORONARY HEART DISEASE

open access: yesРоссийский кардиологический журнал, 2017
Aim. To assess the phenotypes of proinflammatory (M1) and anti-inflammatory (M2) activation of blood monocytes in type 2 diabetes (DM2) comparing to coronary heart disease patients (CHD).Material and methods.
К. О. Galstyan   +5 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Stochastic turbulence modeling in RANS simulations via Multilevel Monte Carlo [PDF]

open access: yes, 2018
A multilevel Monte Carlo (MLMC) method for quantifying model-form uncertainties associated with the Reynolds-Averaged Navier-Stokes (RANS) simulations is presented.
Dwight, Richard P.   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The challenges of using radial inlet guide vanes for wide-range control of a centrifugal compressor [PDF]

open access: yesEPJ Web of Conferences
Regions of significant performance degradation were observed in a single-stage centrifugal compressor tested on a dedicated industrial rig. The machine was operated under discharge throttling, variable impeller speed, and radial inlet guide vane control.
Hurda Lukáš   +2 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Social-Aware Edge Caching in Fog Radio Access Networks

open access: yesIEEE Access, 2017
Fog radio access networks (F-RANs) are becoming an emerging and promising paradigm for fifth generation cellular communication systems. In F-RANs, distributed edge caching techniques among remote radio heads (RRHs) and user equipment (UE) can effectively
Xiang Wang, Supeng Leng, Kun Yang
doaj   +1 more source

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