Results 41 to 50 of about 35,367 (244)

Numerical simulations of airflow in the human pharynx of OSAHS patients

open access: yesCurrent Directions in Biomedical Engineering, 2015
: Computational Fluid Dynamic simulations are performed in real patient individual pharynx geometries of an Obstructive Sleep Apnea patient. The Navier-Stokes equations as well as the Reynolds Averaged Navier-Stokes equations and k − ∊ and k −ω ...
Kluck C., Buzug T.M.
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Who should teach students

open access: yesСеченовский вестник, 2014
In this paper the authors consider the problem of pedagogical skills of teachers of medical schools, analyze the issues related to the quality of teaching various medical specialties.
I. I. Kosarev, R. V. Shurupova
doaj  

Camprarison of different Turbulent Modeling on Rotating Airfoil with Corolios and centrifugal accelaration [PDF]

open access: yesمجله مدل سازی در مهندسی, 2000
The blades moving in a circular path have many industrial applications, these include their use in some turbomachines. In more modern turbo machines, such as jet engine compressors, the flow conditions are completely incompressible.
Iraj Fazeli Farsani, Bahman Asadi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Feasibility Study of Rans in Predicting Propeller Cavitation in Behind-Hull Conditions

open access: yesPolish Maritime Research, 2020
The propeller cavitation not only affects the propulsive efficiency of a ship but also can cause vibration and noise. Accurate predictions of propeller cavitation are crucial at the design stage.
Zhang Yuxin   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Aerodynamic effects of the gap spacing between adjacent vehicles on wind tunnel train models

open access: yesEngineering Applications of Computational Fluid Mechanics, 2020
A certain gap spacing between adjacent vehicles is usually inevitable in wind tunnel force tests of high-speed trains under no crosswind, which may affect the wind tunnel test results.
Yutao Xia   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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