Results 61 to 70 of about 117,677 (282)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Aerodynamic effects of the gap spacing between adjacent vehicles on wind tunnel train models
Engineering Applications of Computational Fluid Mechanics, 2020 A certain gap spacing between adjacent vehicles is usually inevitable in wind tunnel force tests of high-speed trains under no crosswind, which may affect the wind tunnel test results.
Yutao Xia +6 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Flow conditioning downstream a pressure collector
Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2017 In this paper, incompressible turbulent flow downstream a symmetric pressure collector with fixed outlet pipe length is studied. The goal is to obtain smooth axial velocity profile at the outlet plane.
V. A. Kalaev, S. V. Khorobrov
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Hybrid RANS/PDF calculations of sydney swirling flames [PDF]
, 2009 In this work, we perform steady 2D axisymmetric RANS and hybrid RANS/PDF calculations to predict the turbulent flow and mixing fields of swirling inert flows and flames.
De Meester, Reni +2 more
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
New Attitude to the Great Silk Road
Проблемы постсоветского пространства, 2017 The Great Silk Road existed more than 2000 years and has played an important role in the development of civilizations and trade and economic relations.
I. S. Zonn, Uyichtzao Tjan
doaj
Aerodynamic Optimization of 3D Micro HAWT Blade via RSM [PDF]
Journal of Applied Fluid MechanicsThe goal of this research is to redesign the three-dimensional geometry of a micro horizontal-axis wind turbine blade using response surface methodology.
R. Bekkai, R. Mdouki, R. Laouar
doaj +1 more source
Adaptive Embedded LES of the NASA Hump [PDF]
A scheme for adaptive embedded LES is proposed which automatically determines boundaries for LES regions in a hybrid LES-RANS computation, with the goal of minimizing the LES part of the computation for maximum accuracy with minimum cost.
Spalart P., Version V, Woodruff S. L.
core +2 more sources