Results 61 to 70 of about 116,766 (290)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Сеченовский вестник, 2014 In this paper the authors consider the problem of pedagogical skills of teachers of medical schools, analyze the issues related to the quality of teaching various medical specialties.
I. I. Kosarev, R. V. Shurupova
doaj
Feasibility Study of Rans in Predicting Propeller Cavitation in Behind-Hull Conditions
Polish Maritime Research, 2020 The propeller cavitation not only affects the propulsive efficiency of a ship but also can cause vibration and noise. Accurate predictions of propeller cavitation are crucial at the design stage.
Zhang Yuxin +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Aerodynamic effects of the gap spacing between adjacent vehicles on wind tunnel train models
Engineering Applications of Computational Fluid Mechanics, 2020 A certain gap spacing between adjacent vehicles is usually inevitable in wind tunnel force tests of high-speed trains under no crosswind, which may affect the wind tunnel test results.
Yutao Xia +6 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Flow conditioning downstream a pressure collector
Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2017 In this paper, incompressible turbulent flow downstream a symmetric pressure collector with fixed outlet pipe length is studied. The goal is to obtain smooth axial velocity profile at the outlet plane.
V. A. Kalaev, S. V. Khorobrov
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Predicting wind turbine blade loads using vorticity transport and RANS methodologies [PDF]
, 2009 Two computational methods, one based on the solution of the vorticity transport equation, and a second based on the solution of the Reynolds-Averaged Navier-Stokes equations, have been used to simulate the aerodynamic performance of a horizontal axis ...
Brown, Richard +3 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source