Results 311 to 320 of about 315,545 (404)

Mutant Tau (P301L) Enhances Global Protein Translation in Differentiated SH-SY5Y Cells by Upregulating mTOR Signalling. [PDF]

Int J Mol Sci
Cipriano GL, Floramo A, Argento V, Oddo S, Artimagnella O.   +4 more
europepmc   +1 more source

Rapamycin extends life- and health span because it slows aging

, 2013
Mikhail V. Blagosklonny
openalex   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review). [PDF]

Int J Oncol
Pang X, Liu H, Long Y, Wang H.
europepmc   +1 more source

Table S1. 12 genes responsible for temperature sensitivity were determined. from Genetic defects in SAPK signalling, chromatin regulation, vesicle transport and CoA-related lipid metabolism are rescued by rapamycin in fission yeast

, 2018
Kenichi Sajiki, Yuria Tahara, Alejandro Villar‐Briones, Tomáš Pluskal, Takayuki Teruya, Ayaka Mori, Mitsuko Hatanaka, Masahiro Ebe, Takahiro Nakamura, Keita Aoki, Yukinobu Nakaseko, Mitsuhiro Yanagida   +11 more
openalex   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

A Systematic Review of the Efficacy and Safety of Sirolimus (Rapamycin) in the Management of Infantile Hemangioma. [PDF]

J Res Pharm Pract
Abtahi-Naeini B, Ahmadinia F, Ghorbali F, Foroughi E.   +3 more
europepmc   +1 more source

Group 1 mGluR stimulation rescues APOE4-mediated translation defects in neurons. [PDF]

Life Sci Alliance
Radhakrishna BK, Kaladiyil AP, Chakraborty A, Gautam V, Muddashetty RS.   +4 more
europepmc   +1 more source

NOP2/Sun RNA Methyltransferase 4 Regulates the Mammalian Target of Rapamycin Signaling Pathway to Promote Hepatocellular Carcinoma Progression

Congren Wang, Shaoying Ke, Shaoze Lin, Conglin Lin, Zhibing Cai, Lingju Hong, Qunxiong Pan   +6 more
openalex   +1 more source

Mammalian target of rapamycin inhibitors as the treatment for steroid-refractory acute graft-vs.-host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta-analysis. [PDF]

Exp Ther Med
Guo Y, Li Z, Zhang Y, Pan Z, Sun J, Zhang Y, Chang S, Guo Z.   +7 more
europepmc   +1 more source