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RPA Combined With CRISPR/Cas12a for Rapid and Ultrasensitive Detection Dual-Gene of Methicillin-Resistant Staphylococcus aureus (MRSA). [PDF]

J Mol Recognit
Chen L, Luo J, Zhang H, Zhao P.
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Recent advances in rapid antimicrobial susceptibility testing systems

Expert Review of Molecular Diagnostics, 2021
Until recently antimicrobial susceptibility testing (AST) methods based on the demonstration of phenotypic susceptibility in 16-24 h remained largely unchanged.Advances in rapid phenotypic and molecular-based AST systems.AST has changed over the past decade, with many rapid phenotypic and molecular methods developed to demonstrate phenotypic or ...
Michael R. Jacobs, Jordan D. Colson, Daniel D. Rhoads   +2 more
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Blood culture-free ultra-rapid antimicrobial susceptibility testing

Nature
Treatment assessment and patient outcome for sepsis depend predominantly on the timely administration of appropriate antibiotics1-3. However, the clinical protocols used to stratify and select patient-specific optimal therapy are extremely slow4. In particular, the major hurdle in performing rapid antimicrobial susceptibility testing (AST) remains in ...
Tae Hyun Kim, Junwon Kang, Haewook Jang, Hyelyn Joo, Gi Yoon Lee, Hamin Kim, Untack Cho, Hyeeun Bang, Jisung Jang, Sangkwon Han, Dong Young Kim, Chan Mi Lee, Chang Kyung Kang, Pyoeng Gyun Choe, Nam Joong Kim, Myoung-don Oh, Taek Soo Kim, Inho Kim, Wan Beom Park, Sunghoon Kwon   +19 more
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Combinatorial screening SlipChip for rapid phenotypic antimicrobial susceptibility testing

Lab on a Chip, 2022
A combinatorial-screening SlipChip based on a self-partitioning mechanism performs high-throughput phenotypic AST with a panel of antibiotics and antibiotic combinations in three hours by monitoring the phenotypic profile of bacterial growth.
Xiang Li, Xu Liu, Ziqing Yu, Yang Luo, Qixin Hu, Zhenye Xu, Jia Dai, Nannan Wu, Feng Shen   +8 more
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Under-oil open microfluidic systems for rapid phenotypic antimicrobial susceptibility testing

Lab on a Chip, 2023
Under-oil open microfluidic systems (UOMS)-antimicrobial susceptibility testing (AST) integrated with a cloud lab technique provides a versatile platform for rapid phenotypic AST with a sample-to-report turnaround time in around 4 h.
Chao Li, Sue McCrone, Jay W. Warrick, David R. Andes, Zachary Hite, Cecilia F. Volk, Warren E. Rose, David J. Beebe   +7 more
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Gradient-Based Microfluidic Platform for One Single Rapid Antimicrobial Susceptibility Testing

ACS Sensors, 2021
Antimicrobial resistance is a growing problem, necessitating rapid antimicrobial susceptibility testing (AST) to enable effective in-clinic diagnostic testing and treatment. Conventional AST using broth microdilution or the Kirby-Bauer disk diffusion are time-consuming (e.g., 24-72 h), labor-intensive, and costly and consume reagents.
Morteza Azizi, Benyamin Davaji, Ann V. Nguyen, Shiying Zhang, Belgin Dogan, Kenneth W. Simpson, Alireza Abbaspourrad   +6 more
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Rapid Antimicrobial Susceptibility Testing Based on a Bio-Inspired Chemiluminescence Sensor

Analytical Chemistry, 2022
Indiscriminate usage of antibiotics has caused accelerating growth and global expansion of antimicrobial resistance. Therefore, rapid antimicrobial susceptibility testing (AST) for guiding antibiotic prescription and preventing the spread of antimicrobial resistance is in urgent need.
Jidong Wang, Ping Hui, Xinyu Zhang, Xiaoqing Cai, Jie Lian, Xiaolei Liu, Xi Lu, Wenwen Chen   +7 more
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Single-cell morphological analysis for rapid antimicrobial susceptibility test

2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015
A rapid antibiotic susceptibility test (AST) is desperately needed in clinical settings for fast and appropriate antibiotic administration. Traditional ASTs, which rely on cell culture, are not suitable for urgent cases of bacterial infection and antibiotic resistance owing to their relatively long test times.
J. Choi, J. Yoo, M. Lee, E.-G. Kim, J. S. Lee, S. Lee, S. Joo, S. H. Song, E.-C. Kim, J. C. Lee, H. C. Kim, Y.-G. Jung, S. Kwon   +12 more
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