Results 251 to 260 of about 54,644 (329)

DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

open access: yesAdvanced Science, EarlyView.
DeepSecMS, a deep learning platform leveraging a Cys‐to‐Sec proxy training strategy, enhances the identification of known selenoproteins and holds promise for discovering novel candidates. This proxy approach overcomes limitations associated with the rarity of known selenoproteins and demonstrates broad applicability in studying other rare protein ...
Chenfang Si   +5 more
wiley   +1 more source

Advancing Soil Organic Carbon Prediction: A Comprehensive Review of Technologies, AI, Process‐Based and Hybrid Modelling Approaches

open access: yesAdvanced Science, EarlyView.
This review highlights advances in soil organic carbon (SOC) quantification using remote sensing, proximal soil sensing, AI (ML and DL), and biogeochemical modelling. Integrating diverse data sources and models improves SOC prediction accuracy. Key priorities include enhancing data availability, refining models, incorporating microbial processes, and ...
Zijuan Ding   +16 more
wiley   +1 more source

A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication

open access: yesAdvanced Science, EarlyView.
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang   +8 more
wiley   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

open access: yesAdvanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu   +9 more
wiley   +1 more source

Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre‐ and Post‐Implantation Epigenetic Barriers

open access: yesAdvanced Science, EarlyView.
Mammalian cloning via SCNT is limited by several epigenetic barriers. Kdm4d/Kdm5b overexpression plus TSA treatment overcomes epigenetic barriers during pre‐implantation development, while tetraploid complementation replaces defective extraembryonic lineages to bypass H3K27me3 imprinting loss to overcome epigenetic barriers in post‐implantation ...
Yamei Li   +13 more
wiley   +1 more source

An in‐depth Study of the Solid Electrolyte Interphase Compositional Evolution in Sodium‐Ion Batteries: Unravelling the Effects of a Na Metal Counter Electrode on the SEI

open access: yesAdvanced Science, EarlyView.
Compositional evolution of the solid electrolyte interphase in Na‐ion batteries is investigated, focusing on the effects of sodium metal counter electrodes on interphase formation. Advanced analytical techniques are employed to uncover distinct differences in interphase chemistry in half‐cell versus full‐cell configurations.
Jack R. Fitzpatrick   +7 more
wiley   +1 more source

Validity of the Comprehensive Learning Test for Diagnosis of Specific Reading or Mathematical Disorders. [PDF]

open access: yesJ Korean Acad Child Adolesc Psychiatry
Kim S   +9 more
europepmc   +1 more source

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy