Results 61 to 70 of about 953,634 (315)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Rapid Molecular Diagnostic Sensor Based on Ball-Lensed Optical Fibers

Biosensors, 2021
Given the fatal health conditions caused by emerging infectious pathogens, such as severe acute respiratory syndrome coronavirus 2, their rapid diagnosis is required for preventing secondary infections and guiding correct treatments.
Byungjun Park, Bonhan Koo, Jisub Kim, Kiri Lee, Hyeonjin Bang, Sung-Han Kim, Kyung Young Jhang, Yong Shin, Seungrag Lee   +8 more
doaj   +1 more source

Rapid and Accurate Detection of Mycobacterium tuberculosis in Sputum Samples by Cepheid Xpert MTB/RIF Assay-A Clinical Validation Study [PDF]

, 2011
Background: A crucial impediment to global tuberculosis control is the lack of an accurate, rapid diagnostic test for detection of patients with active TB.
Perkins, M., Saathoff, E., Elmar Saathoff, Huggett, J, Zumla, A, Saathoff, E, Rojas-Ponce Gabriel, Andrea Rachow, Reither, K, Mtafya, Bariki, Huggett, J., Klaus Reither, Norbert Heinrich, Heinrich Norbert, Hoelscher Michael, Perkins Mark, Saathoff, Elmar, Mark Perkins, Mtafya, B, Boehme, C, Ntinginya, Elias N., Elias N. Ntinginya, O'Grady, J, Zumla Alimuddin, Saathoff Elmar, O'Grady, Justin, Catharina Boehme, Dheda, Keertan, Boehme Catharina, Ntinginya, EN, Dheda, K., Huggett Jim, Boehme, C., Rachow, A., Elias N Ntinginya, Jim Huggett, Dheda, K, Heinrich, N, Hoelscher, M., Keertan Dheda, Rojas-Ponce, G, Perkins, Mark, Hoelscher, Michael, Mtafya Bariki, Rachow, Andrea, Michael Hoelscher, Heinrich, N., Mtafya, B., Gabriel Rojas-Ponce, Rojas-Ponce, Gabriel, Boehme, Catharina, Perkins, M, Zumla, A., Reither, K., Rachow, A, Bariki Mtafya, Rojas-Ponce G.,, Reither, Klaus, Hoelscher, M, O'Grady J.,, Huggett, Jim, Ntinginya, E. N., O'Grady Justin, Heinrich, Norbert, Rachow Andrea, Reither Klaus, Zumla, Alimuddin, Dheda Keertan, Justin O'Grady, Ntinginya Elias N., Alimuddin Zumla   +70 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Determinants of the accuracy of rapid diagnostic tests in malaria case management: evidence from low and moderate transmission settings in the East African highlands. [PDF]

, 2008
BACKGROUND: The accuracy of malaria diagnosis has received renewed interest in recent years due to changes in treatment policies in favour of relatively high-cost artemisinin-based combination therapies.
Kristan, Mojca, Cox, Jonathan, Michael Okia, Jones Caroline, James Beard, Beard, James, Okia Michael, Caroline Jones, Jones, Caroline, Greenwood, Brian, Brian Greenwood, Rapuoda, Beth, Abeku Tarekegn A, Kristan Mojca, Cox Jonathan, Mojca Kristan, Mueller Dirk H, Dirk H Mueller, Greenwood Brian, Beth Rapuoda, Mueller, Dirk H, Tarekegn A Abeku, Rapuoda Beth, Jonathan Cox, Abeku, Tarekegn A, Okia, Michael, Beard James   +26 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Rapid and accurate viral diagnosis

Pharmacology & Therapeutics, 1989
In recent years, there has been increased recognition of the importance of viral infections. In addition, new antiviral agents have become available. These factors have led to a marked increase in utilization of viral diagnostic services. In this review, both conventional and rapid methods for viral diagnosis are presented, with emphasis on recent ...
Landry, M.L., Mayo, D.R., Hsiung, G.D.
openaire   +2 more sources

Health workers' use of malaria rapid diagnostic tests (RDTs) to guide clinical decision making in rural dispensaries, Tanzania. [PDF]

, 2010
Rapid diagnostic tests (RDTs) were developed as an alternative to microscopy for malaria diagnosis. The RDTs detect malaria parasite antigen(s) in whole blood with high sensitivity and specificity.
M. Irene Masanja, McMorrow, Meredith, Kachur, S Patrick, Peter D. McElroy, S. Patrick Kachur, McElroy, Peter D, Meredith McMorrow, Masanja, M Irene, Kahigwa, Elizeus, Elizeus Kahigwa   +9 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source