Results 91 to 100 of about 1,045,227 (267)

Reliability of Rapid Diagnostic Tests in Diagnosing Pregnancy-Associated Malaria in North-Eastern Tanzania. [PDF]

, 2012
Accurate diagnosis and prompt treatment of pregnancy-associated malaria (PAM) are key aspects in averting adverse pregnancy outcomes. Microscopy is the gold standard in malaria diagnosis, but it has limited detection and availability.
A Mayor, A Moody, A Muehlenbachs, A Salanti, AA Adegnika, Adrian JF Luty, AE Mnzava, AHD Kilian, AJ Umbers, Ali Salanti, AM de Oliveira, B Mmbando, C Wongsrichanalai, Caroline Pehrson, CE Shulman, CE Shulman, Christentze Schmiegelow, D Ishengoma, Daniel Andersen, Daniel TR Minja, Davis John, DP Mason, DR Bell, DRS Ishengoma, E Tjitra, F Bánhidy, F Mockenhaupt, FP Mockenhaupt, FP Mockenhaupt, G Snounou, H Reyburn, H Verhoef, HL Guyatt, IA McGregor, J Baker, J Lusingu, J Wooden, JM Tham, John PA Lusingu, JP Lusingu, JR Forney, K Källander, KA Bojang, LC Okell, LEG Mboera, LM Singer, M Amexo, M Dhorda, M Fried, M Fried, M Mayxay, M Mayxay, Martha Lemnge, Mayke Oesterholt, Michael Alifrangis, ML McMorrow, N Othnigué, NEER Singh, NJ White, P Bejon, P Mens, P Mens, Pamela A Magistrado, PE Duffy, Philippe Deloron, R Bǿdker, RW Steketee, S Gerstl, S Karl, S Schachterle, Stéphanie Boström, T Jelinek, TA VanderJagt, The United Republic of Tanzania, Thor Theander, TT Thomsen, V Batwala, WHO   +77 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Demonstrasi Kehadiran Protein Permukaan Sel Yang Antigenik Dan Spesifik Untuk Shigella Spp. Dan Pembangunan Ke Arah Ujian Diagnostik Segera Bagi Penyakit Shigelosis [PDF]

, 2001
Shigella spp. is the major etiologic agent of dysentery or bloody diarrhoea in humans. It has been identified as an important cause for morbidity and mortality among children especially in developing countries. Early diagnosis of shigellosis is the major
Kirnpal Kaur, Banga Singh
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

PEMERIKSAAN MIKROSKOP DAN TES DIAGNOSTIK CEPAT DALAM MENEGAKKAN DIAGNOSIS MALARIA

e-Jurnal Medika Udayana, 2014
Malaria is an infection disease caused by plasmodium parasite that transmitted to humanbody by female anopheles mosquito bites. World Health Organization (WHO) predictedthat 3,3 billion people around the world were at risk to infected by malaria in 2006 ...
Wijaya Kusuma, A.A. Wiradewi Lestari, Sianny Herawati, I Wayan Putu Sutirta Yasa   +3 more
doaj  

Use of a highly-sensitive rapid diagnostic test to screen for malaria in pregnancy in Indonesia

Malaria Journal, 2020
Background The sensitivity of rapid diagnostic tests (RDTs) for malaria is inadequate for detecting low-density, often asymptomatic infections, such as those that can occur when screening pregnant women for malaria.
Vera T. Unwin, Rukhsana Ahmed, Rintis Noviyanti, Agatha M. Puspitasari, Retno A. S. Utami, Leily Trianty, Theda Lukito, Din Syafruddin, Jeanne R. Poespoprodjo, Maria A. Santana-Morales, Feiko O. Ter Kuile, Emily R. Adams   +11 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Rapid detection of white spot syndrome virus (WSSV) of Penaeus monodon by latex agglutination test using monoclonal antibodies [PDF]

, 2006
Latex beads were sensitized with monoclonal antibodies (MAb) rose against VP28 of WSSV. The optimum concentration of MAb required to sensitize the latex beads was 125 µg/ml.
Chandramohan, A., Chandran, N.D.J., Koteeswaran, A., Makesh, M., Manohar, B.M., Mukherjee, S.C., Raman, R.P., Ramasamy, V.   +7 more
core  

Dilution testing using rapid diagnostic tests in a HIV diagnostic algorithm: a novel alternative for confirmation testing in resource limited settings. [PDF]

, 2015
BACKGROUND: Current WHO testing guidelines for resource limited settings diagnose HIV on the basis of screening tests without a confirmation test due to cost constraints. This leads to a potential risk of false positive HIV diagnosis.
Abebe, Almaz, Ariti, Cono, Klarkowski, Derryck, Masiga, Johnson, Muluneh, Libsework, Pearce, Neil, Piriou, Erwan, Ritmeijer, Koert, Shanks, Leslie, Siddiqui, M Ruby, Wazome, Joseph   +10 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source