Results 51 to 60 of about 1,840,121 (280)

Solidification characteristics of Fe-Ni peritectic alloy thin strips under a near-rapid solidification condition [PDF]

open access: yesChina Foundry, 2015
This paper is an experimental investigation of the structure evolution and the solute distribution of 2 mm thick strips of Fe-(2.6, 4.2, 4.7, 7.9wt.%)Ni peritectic alloy under a near-rapid solidification condition, which were in the regions of δ-ferrite ...
Chang-jiang Song, Yang Yang, Yuan-yi Guo
doaj  

Non- and Quasi-Equilibrium Multi-Phase Field Methods Coupled with CALPHAD Database for Rapid-Solidification Microstructural Evolution in Laser Powder Bed Additive Manufacturing Condition

open access: yesMetals, 2021
A solidification microstructure is formed under high cooling rates and temperature gradients in powder-based additive manufacturing. In this study, a non-equilibrium multi-phase field method (MPFM), based on a finite interface dissipation model, coupled ...
Sukeharu Nomoto   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Traveling waves in rapid solidification

open access: yesElectronic Journal of Differential Equations, 2000
We analyze rigorously the one-dimensional traveling wave problem for a thermodynamically consistent phase field model. Existence is proved for two new cases: one where the undercooling is large but not in the hypercooled regime, and the other for waves ...
Karl Glasner
doaj  

Achieving the coexistence of multiple strengthening mechanisms in a dual-phase Mg-Li via rapid solidification

open access: yesJournal of Magnesium and Alloys
The insufficient absolute strength of Mg-Li alloys severely restricts their aerospace applications. To address this limitation, a dual-phase Mg-Li alloy with enhanced strength was fabricated through rapid solidification combined with hot-press sintering ...
Xianzhe Shi   +6 more
doaj   +1 more source

A Critical Review on Al-Co Alloys: Fabrication Routes, Microstructural Evolution and Properties

open access: yesMetals, 2022
Al-Co alloys is an emerging category of metallic materials with promising properties and potential application in various demanding environments. Over the years, different manufacturing techniques have been employed to fabricate Al-Co alloys, spanning ...
Athanasios K. Sfikas   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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