Results 131 to 140 of about 13,667 (153)
Rare and unknown actinobacteria from unexplored environments have the potential to produce new bioactive molecules. This study aimed to use 16 s rRNA metabarcoding to determine the composition of the actinobacterial community, particularly focusing on rare and undescribed species, in a nature reserve within the Brazilian Cerrado called Sete Cidades ...
Leonardo Bandeira +2 more
exaly +4 more sources
Angiogenesis is a physiological process that has important impacts on the pathology and healing of various diseases, and its induction or inhibition by bioactive actinobacterial metabolites can help the treatment of some diseases. In this study, the effects of actinobacterial extract in the process of angiogenesis have been explored.In this research ...
Yousef Azarakhsh +2 more
exaly +4 more sources
Sanghee Kim, Jun Hyuck Lee, Se Jong Han
exaly +3 more sources
A rare actinobacteria strain designated SCA21, producing bioactive metabolites was isolated from marine sediment of Havelock Island, Andaman and Nicobar Islands, India. Analysis of 16S rRNA sequences suggested that the strain SCA21 belonged to the genus Nocardiopsis.
Ravishankar Rai Vittal
exaly +4 more sources
Cultivation Techniques of Rare Actinobacteria
Vijayakumar Ramasamy +3 more
openalex +2 more sources
Glutathione: A powerful but rare cofactor among Actinobacteria
Glutathione (γ-l-glutamyl-l-cysteinylglycine, GSH) is a powerful cellular redox agent. In nature only the l,l-form is common among the tree of life. It serves as antioxidant or redox buffer system, protein regeneration and activation by interaction with thiol groups, unspecific reagent for conjugation during detoxification, marker for amino acid or ...
Anna C. Lienkamp +2 more
openalex +3 more sources
Rare taxa and dark microbial matter: novel bioactive actinobacteria abound in Atacama Desert soils
An "in house" taxonomic approach to drug discovery led to the isolation of diverse actinobacteria from hyper-arid, extreme hyper-arid and very high altitude Atacama Desert soils. A high proportion of the isolates were assigned to novel taxa, with many showing activity in standard antimicrobial plug assays. The application of more advanced taxonomic and
Michael Goodfellow +4 more
openalex +3 more sources
Vascular calcification (VC) is a significant pathological process in some life-threatening diseases. Several pathological mechanisms, including transdifferentiation of vascular smooth muscle cells to osteoblast-like cells and apoptosis are involved in VC. Compounds with an inhibitory effect on these processes are potentially efficient medications.
Fatemeh Salimi +3 more
openalex +3 more sources
Cytotoxic Angucyclines fromAmycolatopsissp. HCa1, a Rare Actinobacteria Derived fromOxya chinensis
Two new angucyclines, named (2R,3R)-2-hydroxy-8- O-methyltetrangomycin (1) and (2R,3R)-2-hydroxy-5-O-methyltetrangomycin (2), together with eight known compounds (3-10), were isolated from the culture of Amycolatopsis sp. HCa1, a rare actinobacteria isolated from the gut of Oxya chinensis.
Zhi Kai Guo +5 more
openalex +3 more sources

