Results 181 to 190 of about 486,973 (258)

Quantifying the fidelity of in vitro human cell culture systems using a biomedical foundation model. [PDF]

Proc Natl Acad Sci U S A
Fujii S, Espenschied ST, Anand V, Bettencourt-Silva J, Han Y, Ito G, Koseki A, Kosugi A, Kozloski J, Matsumoto R, Meng S, Mulligan N, Musich RJ, Newhall KP, Oshina E, Sekiguchi S, Wang Y, Hu J, Ciorba M, Sibley LD, Okamoto R, Stappenbeck TS.   +21 more
europepmc   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Cell-type-specific alternative splicing in the brain and kidney of a Setbp1S858R Schinzel-Giedion syndrome mouse.

Dis Model Mech
Soelter TM, Jones EF, Howton TC, Crumley AB, Wilk EJ, Lasseigne BN.   +5 more
europepmc   +1 more source

Robust characterization and interpretation of rare pathogenic cell populations from spatial omics using GARDEN. [PDF]

Nat Commun
Zhang X, Yu Z, Hao G, Yao Q, Hu Y, Wang F, Chen X, Liu L, Wong KC, Li X.   +9 more
europepmc   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Organelle Localization‐Induced Bio‐Orthogonal Polymerization (OLIBOP) for Photostable Super‐Resolution Live‐Cell Imaging

Advanced Healthcare Materials, EarlyView.
Organelle localization‐induced biorthogonal polymerization enables direct synthesis of photostable poly‐AIEgens within targeted organelles for super‐resolution live‐cell imaging. ABSTRACT Real‐time monitoring of dynamic biological processes demands fluorescent probes that can withstand prolonged light exposure without photobleaching—a critical ...
Gaeun Park, Sangpil Kim, Dohyun Kim, Injun Hwang, Ja‐Hyoung Ryu   +4 more
wiley   +1 more source

A rare pelvic mass in an adult woman: case report of a mature sacrococcygeal teratoma. [PDF]

J Surg Case Rep
Guennouni A, Laasri I, Bahha S, Omor Y, Latib R, Amalik S.   +5 more
europepmc   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

A Rare Case of Poorly Differentiated Lower Esophageal Cancer with Neuroendocrine Differentiation and α-Fetoprotein Production. [PDF]

Surg Case Rep
Takii M, Takemura M, Oshima T, Yamada M, Inazu D, Miyamoto H, Yamaguchi H.   +6 more
europepmc   +1 more source