Results 251 to 260 of about 1,474,638 (301)
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Current Opinion in Cell Biology, 1996
The search for proteins which interact with the active GTP-bound form of Ras in order to transmit signals for proliferation, differentiation and oncogenesis has been a long one. Now there are several strong candidates for Ras effectors that include protein kinases, lipid kinases and guanine nucleotide exchange factors. Structural information on how one
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The search for proteins which interact with the active GTP-bound form of Ras in order to transmit signals for proliferation, differentiation and oncogenesis has been a long one. Now there are several strong candidates for Ras effectors that include protein kinases, lipid kinases and guanine nucleotide exchange factors. Structural information on how one
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Oncology Reports, 1996
A number of proteins and low-molecular weight compounds have been reported to suppress the activity toward ras-oncogenes and their products. These include anti-lias antibody, inhibitors of Ras activation, Ras dominant negative mutants, inhibitors of processing of newly-synthesized Ras, suppressors and inhibitors of downstream effecters and genetic ...
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A number of proteins and low-molecular weight compounds have been reported to suppress the activity toward ras-oncogenes and their products. These include anti-lias antibody, inhibitors of Ras activation, Ras dominant negative mutants, inhibitors of processing of newly-synthesized Ras, suppressors and inhibitors of downstream effecters and genetic ...
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2006
Ras proteins (H-, N-, and K-Ras) are critical components of signal transduction pathways leading from cell-surface receptors to the control of cell proliferation, differentiation or death. Normal Ras proteins exist in equilibrium between an active (Ras-GTP) and an inactive (Ras-GDP) state.
Jose M. Rojas, Eugenio Santos
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Ras proteins (H-, N-, and K-Ras) are critical components of signal transduction pathways leading from cell-surface receptors to the control of cell proliferation, differentiation or death. Normal Ras proteins exist in equilibrium between an active (Ras-GTP) and an inactive (Ras-GDP) state.
Jose M. Rojas, Eugenio Santos
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JAMA: The Journal of the American Medical Association, 1981
M A, Shampo, R A, Kyle
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M A, Shampo, R A, Kyle
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RAS-targeted therapies: is the undruggable drugged?
Nature Reviews Drug Discovery, 2020Amanda R Moore +2 more
exaly
2017
As RNA sequencing (RNA-Seq) becomes more affordable to process, the number of sequencing data has increased at a rapid rate. A major challenge in RNA-Seq experiments is the analysis of large amount of data generated by next-generation sequencing. RNA-Seq data analysis usually requires advanced Linux/Unix experience for software installation and tedious
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As RNA sequencing (RNA-Seq) becomes more affordable to process, the number of sequencing data has increased at a rapid rate. A major challenge in RNA-Seq experiments is the analysis of large amount of data generated by next-generation sequencing. RNA-Seq data analysis usually requires advanced Linux/Unix experience for software installation and tedious
openaire +1 more source