Results 141 to 150 of about 370,587 (208)

Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors. [PDF]

Nat Commun
Bonsor DA, Finci LI, Potter JR, Young LC, Wall VE, Goldstein de Salazar R, Geis KR, Stephens T, Finney J, Nissley DV, McCormick F, Simanshu DK.   +11 more
europepmc   +1 more source

Resolution of distinct steps in mitochondrial protein import [PDF]

, 1988
Bradshaw, Ralph A., Douglas, M. G., Hartl, Franz-Ulrich, McAlister-Henn, L., Neupert, Walter, Pfanner, Nikolaus   +5 more
core  

Positive cooperativity between RAS-binding and cysteine-rich domains regulates RAF membrane binding kinetics via lateral rebinding. [PDF]

Nat Commun
Jimenez Salinas A, Tevdorashvili K, Grim J, Morales A, Chakhrakia A, Kwang Lee Y.   +5 more
europepmc   +1 more source

A highly promising new avenue for targeting K-RAS: The small-molecule degrader XMU-MP-9. [PDF]

Acta Pharm Sin B
Jin J.
europepmc   +1 more source

Exploring the Pleiotropic Cardioprotective Effects of GLP-1 Receptor Agonists in Preventing Anthracycline-Induced Cardiotoxicity: A Theoretical Proposal for Future Research. [PDF]

Medicines (Basel)
Repp ML, Chinyere IR, Teran S, Bast J, Kondapalli L.   +4 more
europepmc   +1 more source

Physalin A Suppresses Human Oral Squamous Carcinoma Cell Migration and Invasion Through Inhibiting Grb2/Ras and MMP/uPA Signaling Pathways. [PDF]

In Vivo
Ma YS, Chueh FS, Kuo YH, Hsieh YS, Yu SN, Chen JY, Lin WY, Chen JC, Chen CY, Hsieh WT, Huang YP.   +10 more
europepmc   +1 more source

Renin-angiotensin system blockade attenuates brain mitochondrial dysfunction, oxidative stress, and neuroinflammation associated with hypertension, metabolic disorders, and aging. [PDF]

World J Exp Med
García Menéndez S, Inserra F, de Cavanagh EM, Ferder L, Manucha W.   +4 more
europepmc   +1 more source

KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics. [PDF]

J Biol Chem
Georgouli K, Tempkin JOB, Stanton LG, Oppelstrup T, Shrestha R, Carpenter TS, Aydin F, Zhang X, Bhatia H, Yang Y, Van QN, Bonilla PA, Gulten G, Goswami D, Di Natale F, Chavez JR, Moon JY, Dharuman G, Hengartner NW, Simanshu DK, Tran TH, Nguyen K, Stanley CB, Van Essen B, Bremer PT, Lightstone FC, Stephen AG, Glosli JN, Gnanakaran S, Turbyville TJ, McCormick F, Nissley DV, Streitz FH, Ingólfsson HI.   +33 more
europepmc   +1 more source

KRAS Inhibitors in Pancreas Cancer: Facts and Hopes about the Immunotherapy We've All Been Waiting For. [PDF]

Clin Cancer Res
Stanger BZ, Vonderheide RH.
europepmc   +1 more source

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review). [PDF]

Int J Oncol
Aloliqi AA, Alnuqaydan AM, Alshebremi M, Rahmani AH, Khan AA.   +4 more
europepmc   +1 more source