Results 121 to 130 of about 5,283,585 (380)

A Gathering For Gardner Puzzle-Game [PDF]

open access: yes, 2017
Each different letter of GATHERING FOR GARDNER is used exactly three times in the following words: DIE, FAD, FIT, FOG, GIN, HAG, HER, HOD, NOR, RAT ...
Farrell, Jeremiah, Morgan, Chris
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Do Perceptions About the Causes of Poverty and Wealth Shape Attitudes Towards Progressive Taxation? An Exploratory Analysis for 2021 Romania

open access: yesStudia Universitatis Babes-Bolyai Sociologia
Lying at the backbone of European welfare states, taxation is both an enabler of redistribution and a predilect means of fiscal welfare. Among Central and Eastern European countries, Romania was an early adopter of flat rate taxation two decades ago, in ...
Dragoman Diana, Raţ Cristina
doaj   +1 more source

Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide [PDF]

open access: yes, 2001
Background: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect
Baxter, G.F.   +5 more
core  

The Pomace Extract Taurisolo Protects Rat Brain From Ischemia-Reperfusion Injury

open access: gold, 2020
Dominga Lapi   +9 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Generation and characterization of a humanized ACE2 rat model for the study of SARS-CoV-2 and COVID-19

open access: yesFrontiers in Microbiology
Our goal was to generate new rat strains for the study of human pathogenic viruses such as SARS-CoV-2 that use ACE2 for entry into host cells. An over-expression rat model was generated using random transgenesis to integrate copies of human ACE2 under ...
Rachel M. Olson   +13 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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