Results 151 to 160 of about 5,283,585 (380)

Automated Chaos-Driven S-Box Generation and Analysis Tool for Enhanced Cryptographic Resilience

IEEE Access
In a rapidly advancing world of technology, information security studies have become the backbone of the digital age, and steps in this area are critical.
Yilmaz Aydin, Fatih Ozkaynak
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Flower Automata Pattern-Based Discrimination of Fibromyalgia From Control Subjects Using Fusion of Sleep EEG and ECG Signals

IEEE Access
Electroencephalogram (EEG) and electrocardiogram (ECG) signals provide vital insights into brain and heart activity and are widely used in automated medical diagnostics. This study introduces a novel, multimodal fibromyalgia detection system developed by
Prabal Datta Barua, Makiko Kobayashi, Sengul Dogan, Mehmet Baygin, Turker Tuncer, Jose Kunnel Paul, Thomas Iype, U. R. Acharya   +7 more
doaj   +1 more source

Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: an electrophysiological and modelling study

, 2006
Jacopo Magistretti, Loretta Castelli, Lia Forti, Egidio D’Angelo   +3 more
openalex   +1 more source

Effects of Hypoxia on Glucose, Insulin, Glucagon, and Modulation by Corticotropin-Releasing Factor Receptor Type 1 in the Rat [PDF]

, 2007
Xuequn Chen, Jing Dong, Chen-Ying Niu, Junming Fan, Ji-Zeng Du   +4 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Interglacial refugia on tropical mountains: Novel insights from the summit rat (Rattus baluensis), a Borneo mountain endemic [PDF]

, 2018
Miguel Camacho‐Sanchez, Irene Quintanilla, Melissa T. R. Hawkins, Fred Tuh, Konstans Wells, Jesús E. Maldonado, Jennifer A. Leonard   +6 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Endogenous Chemerin from PVAT Amplifies Electrical Field-Stimulated Arterial Contraction: Use of the Chemerin Knockout Rat [PDF]

, 2020
Emma D Flood, Stephanie W. Watts
openalex   +1 more source