Results 171 to 180 of about 1,841,501 (298)

UHPLC/MS Profile and Antimalarial Potency of <i>Enantia chlorantha</i> Oliv. (Annonaceae) Stem Bark Aqueous Extract. [PDF]

Adv Pharmacol Pharm Sci
Messi Betene AN, Gounoue Kamkumo R, Tsouh Fokou PV, Ngueguim Tsofack F, Mbock MA, Madiesse Kemgne EA, Ngako A, Ngwem Tenlep LS, Tsakem Nangap MJ, Fokou R, Dize D, Owona P, Tchatat Tali MB, Fekam Boyom F, Dimo T.   +14 more
europepmc   +1 more source

[Ca2+]i elevations detected by BK channels during Ca2+ influx and muscarine-mediated release of Ca2+ from intracellular stores in rat chromaffin cells.

, 1996
Murali Prakriya, Christopher R. Solaro, Christopher J. Lingle   +2 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Interdisciplinary Approach at the Border Between Hematology and Cardiology

Journal of Interdisciplinary Medicine, 2017
Opincariu Diana, Rat Nora
doaj   +1 more source

Magnetic dipole imaging of magnetite nanoparticles in brain tissue. [PDF]

RSC Adv
Kaub L, Gilder SA, Fu RR, Maher BA, Maxemin G, Kuan AT, Büttner A, Milz S, Schmitz C.   +8 more
europepmc   +1 more source

Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues [PDF]

, 1989
PW Mantyh, Taylor Gates, C.R. Mantyh, JE Maggio   +3 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Rat Spine Fusion Models for Preclinical Research: Opportunities and Challenges. [PDF]

ACS Biomater Sci Eng
Lobao A, Rice SW, Chapman J, Stauff MP, Song J.   +4 more
europepmc   +1 more source

Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat [PDF]

, 1982
Emanuele Albano, K. A. K. Lott, T. F. Slater, A. Stier, M. C. R. Symons, Aldo Tomasi   +5 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source