Results 171 to 180 of about 1,864,302 (297)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

6-Nitrodopamine Potentiates Catecholamine-Induced Ca²⁺ _i Release in Human Aortic Smooth Muscle and Modulates Vascular Smooth Muscle Contractility. [PDF]

Basic Clin Pharmacol Toxicol
Britto-Júnior J, Lima AT, Qiao S, Tang HF, Cardenas V, Antunes E, De Nucci G, Ferro A.   +7 more
europepmc   +1 more source

Correction to “Identification of copper/zinc superoxide dismutase as a novel nitric oxide‐regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats” [PDF]

openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Effects of nonsteroidal anti-inflammatory drugs on glutathione S- transferases of the rat digestive tract [PDF]

, 1997
Emile van Lieshout
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Influence du statut en magnésium, calcium et vitamine D sur l'homéostasie du calcium et l'expression de gènes dépendant de la 1,25-dihydroxyvitamine D3 chez le rat

, 1993
Lemay, Jacques
openalex   +1 more source

Regulation of Rat Dopamine Transporter mRNA and Protein by Chronic Cocaine Administration [PDF]

, 1999
Sharon R. Letchworth, Tom Sexton, Steven R. Childers, Kent E. Vrana, Roxanne A. Vaughan, Huw M. L. Davies, Linda J. Porrino   +6 more
openalex   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Ketogenic diet sex-dependent effects on rat bone marrow cells during development and β-HB protection in hypoglycemia. [PDF]

Sci Rep
Truchan K, Ilnicki B, Setkowicz Z, Osyczka AM.   +3 more
europepmc   +1 more source