Results 31 to 40 of about 5,906 (214)

Light‐Driven Out‐of‐Equilibrium Helicity Control in a Diarylethene–Helicene Photosystem

Angewandte Chemie, EarlyView.
Distinct energy landscapes of different helicities in the open and closed states of a diarylethene–helicene photoswitch enable a light‐driven energy ratchet. Helix inversion occurs selectively in the closed form, and the resulting helicity is transferred and kinetically trapped upon ring opening, generating a persistent out‐of‐equilibrium chiral state ...
Eric Sidler, Jinghao Wang, Christina Vallina, Ben L. Feringa   +3 more
wiley   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Biomechanical investigation of a novel ratcheting arthrodesis nail

Journal of Orthopaedic Surgery and Research, 2010
Background Knee or tibiotalocalcaneal arthrodesis is a salvage procedure, often with unacceptable rates of nonunion. Basic science of fracture healing suggests that compression across a fusion site may decrease nonunion.
Billiar Kristen L, Weiss Douglas R, Li Xinning, McCormick Jeremy J, Wixted John J   +4 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Experimental and Numerical Analysis of Ratcheting Behavior of Super Duplex SAF2507 Stainless Steel Under Uniaxial Loading

Applied Sciences
Super duplex SAF2507 stainless steel is widely used in petrochemical piping systems during the transport of substances. The pipelines are subjected to cyclic loads due to road vibration and internal pressure, which causes the ratcheting behavior. In this
Hongru Liu, Xiaohui Chen, Xiaoyue Zhang, Xiaodong Cui   +3 more
doaj   +1 more source

Experimental and Computational Approach to Fatigue Behavior of Polycrystalline Tantalum

Metals, 2021
This work provides an experimental and computational analysis of low cycle fatigue of a tantalum polycrystalline aggregate. The experimental results include strain field and lattice rotation field measurements at the free surface of a tension–compression
Damien Colas, Eric Finot, Sylvain Flouriot, Samuel Forest, Matthieu Mazière, Thomas Paris   +5 more
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Design of a Multistable Finger Prosthesis with Programmable Metamaterials

Advanced Engineering Materials, EarlyView.
This research article shows the development of a multistable programmble metamaterial for the use as a finger prosthesis. The material was designed on different hierarchical levels where the influence of geometrical parameters and combination of mechanical elements was explored.
Franziska Wenz, Jannik Krohn, Alexander Leichner, Dilip Chalissery, Heiko Andrae, Chris Eberl   +5 more
wiley   +1 more source

Study on ratcheting of beams under the combination of gravity and seismic load

Mechanical Engineering Journal, 2019
Ratcheting is one common phenomenon under excessive earthquakes. This study focuses on clarifying the ratcheting mechanism of beams subjected to the combination of gravity and seismic loadings. The sinusoidal excitations or their combinations represented
Jinqi LYU, Masakazu ICHIMIYA, Md Abdullah Al BARI, Ryunosuke SASAKI, Naoto KASAHARA   +4 more
doaj   +1 more source