Results 111 to 120 of about 2,841,411 (301)
DETERMINANT FACTORS FOR FERTILITY. CASE OF ALBANIA [PDF]
Fertility Rates in Albania have suffered a great change over the past 20 years. Starting from this fact the main objective of this study is to investigate the relation between fertility rate and its determinant factors.
Arjan Tushaj, Valentina Sinaj
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Decline in Youth Participation in Canada in the 1990s: Structural or Cyclical? [PDF]
Of the three major age groups, youth (aged 15-24), experienced the largest fall in labour force participation and accounted for the lion’s share of the aggregate decline.
Andrew Sharpe +3 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Applied SciencesThe aim of this study was to compare the braking and propulsion force–time and barbell velocity characteristics between back squat sets performed using traditional (TRAD) or accentuated eccentric loading (AEL) in resistance-trained women.
Brookelyn A. Campbell +7 more
doaj +1 more source
Reactive Strength Index Modified Is a Valid Measure of Explosiveness in Collegiate Female Volleyball Players [PDF]
, 2016 Kipp, K, Kiely, MT, and Geiser, CF. Reactive strength index modified is a valid measure of explosiveness in collegiate female volleyball players. J Strength Cond Res 30(5): 1341–1347, 2016—The purpose of this study was to investigate the validity of the ...
Geiser, Christopher +2 more
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Labour Market Dynamics in Pakistan: Evidence from the Longitudinal Data [PDF]
The bulk of research on labour market conditions in Pakistan has concentrated on the economic activity rate, the number of employed persons, or the unemployment rate at a particular point in time.
G. M. Arif +2 more
core
Youth and the Labor Force: Background and Trends [PDF]
, 2018 [Excerpt] This report provides current and historical labor force information about young people ages 16 to 24. In general, youth have a lower rate of labor force participation, and those who are in the labor force are less likely to gain employment than
Fernandes-Alcantara, Adrienne L
core +1 more source