Results 91 to 100 of about 489,800 (291)
Reputation as an Entry Barrier in the Credit Rating Industry [PDF]
We study competition between an incumbent Credit Rating Agency (CRA) and a sequence of entrant CRAs that are potentially more e¤ective but whose ability in appraising default risk is unproven when they enter the market.
Jeon, Doh-Shin, Lovo, Stefano
core
Rating Agencies: Is There an Agency Issue? [PDF]
, 2002 This paper examines the potential for conflicts of interest in the debt ratings business. Inherent in the current business model is the fact that firms whose obligations are rated by the agencies pay fees for those ratings, which in turn comprises virtually all of the revenues of the rating agencies.
Roy C. Smith, Ingo Walter
openaire +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Are Bank Ratings Coherent with Bank Default Probabilities in Emerging Market Economies ? [PDF]
In this paper we investigate the coherence between bank ratings and default probability in emerging market economies using scoring and mapping techniques.
Christophe Godlewski
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Perceptions of the implementation of credit rating agency regulation in South Africa
South African Journal of Economic and Management SciencesBackground: Credit rating agencies (CRA) played a key role in the global financial crises of 2007/2008 which led to the introduction of CRA regulation. Aim: Using Giddens’ theory of modernity as a framework, this article analyses experts’ perceptions of
David Rabinowitz +3 more
doaj +1 more source
Do institutions matter for technological change in transition economies? The case of the Russia's 89 regions and republics [PDF]
, 2006 We explore the impact of institutions on technological change in a transition economy. We use regional panel data for Russia's 89 regions and republics during the period of recovery and growth from 1998 to 2004 to show the impact of large variation in ...
Granville, B., Leonard, C.S.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source