Results 111 to 120 of about 3,914,003 (294)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Comparison of phase-coherent and non-phase- coherent coded communications [PDF]

open access: yes
Word-error probability versus signal-to-noise ratio evaluation for five communications ...
Saliga, T. V., Strong, J. P., III
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Jamming modulation aided anti-jamming communication method based on optimized bit error ratio

open access: yesTongxin xuebao
To enhance the communication’s anti-suppressive jamming capability, a jamming modulation aided anti-jamming communication method based on optimized bit error ratio (BER) was proposed. Firstly, the system model of jamming modulation aided anti-jamming was
Zhang Yusi   +4 more
doaj  

Predictive Performance Evaluation of ARIMA and Hybrid ARIMA-LSTM Models for Particulate Matter Concentration

open access: yesJOIN: Jurnal Online Informatika
This study provides an objective evaluation of prediction performance models for particulate matter policy for industrial stakeholders by comparing the ARIMA and Hybrid ARIMA-LSTM models for predicting air quality data from the industrial environment. In
Johanes Dian Kurniawan   +2 more
doaj   +1 more source

The design and analysis of single flank transmission error testor for loaded gears [PDF]

open access: yes
Due to geometrical imperfections in gears and finite tooth stiffnesses, the motion transmitted from an input gear shaft to an output gear shaft will not have conjugate action.
Bassett, D. E., Houser, D. R.
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

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