Results 61 to 70 of about 3,892,702 (296)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Performance analysis of amplify-and-forward cooperative communication systems with imperfect channel estimation

open access: yesTongxin xuebao, 2011
The impact of channel estimation errors on the performance for two-hop multi-relays assisted am-plify-and-forward(AF) cooperative communication systems was investigated.Closed-form expressions of the average symbol error rate,as well as the diversity ...
WANG Lei   +3 more
doaj   +2 more sources

Minimize the Prediction Error in External Consensus Problem using Gain Error Ratio Formula

open access: yesApplications of Modelling and Simulation, 2017
This paper discusses the external consensus problem for non-identical networked multi-agent systems (NMAS) with network data loss, considering uniform consecutive data losses (CDL) induced by long periods of transmission failure. A gain error ratio (GER)
Nurul Adilla Mohd Subha   +2 more
doaj  

Quantum key distribution over 122 km of standard telecom fiber

open access: yes, 2004
We report the first demonstration of quantum key distribution over a standard telecom fiber exceeding 100 km in length. Through careful optimisation of the interferometer and single photon detector, we achieve a quantum bit error ratio of 8.9% for a ...
A. J. Shields   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Measuring of Block Error Rates in High-Speed Digital Networks

open access: yesAdvances in Electrical and Electronic Engineering, 2006
Error characteristics is a decisive factor for the digital networks transmission quality definition. The ITU – TG.826 and G.828 recommendations identify error parameters for high – speed digital networks in relation to G.821 recommendation.
Petr Ivaniga, Ludovit Mikus
doaj  

A method of back-calculating the log odds ratio and standard error of the log odds ratio from the reported group-level risk of disease.

open access: yesPLoS ONE, 2020
In clinical trials and observational studies, the effect of an intervention or exposure can be reported as an absolute or relative comparative measure such as risk difference, odds ratio or risk ratio, or at the group level with the estimated risk of ...
Dapeng Hu   +2 more
doaj   +1 more source

Optimal ratio between phase basis and bit basis in QKD

open access: yes, 2008
In the original BB84 protocol, the bit basis and the phase basis are used with equal probability. Lo et al (J. of Cryptology, 18, 133-165 (2005)) proposed to modify the ratio between the two bases by increasing the final key generation rate. However, the
C. H. Bennett   +6 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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