Results 81 to 90 of about 3,914,003 (294)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Divergent estimation error in portfolio optimization and in linear regression

open access: yes, 2007
The problem of estimation error in portfolio optimization is discussed, in the limit where the portfolio size N and the sample size T go to infinity such that their ratio is fixed. The estimation error strongly depends on the ratio N/T and diverges for a
B. Scherer   +12 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

E2/M1 ratio from the Mainz $p(\vec \gamma, p)\pi^0$ data

open access: yes, 1997
We suggest that the error quoted in the Mainz determination of the E2/M1 ratio (at the resonance energy) should be enlarged. A term dropped in expressions used by this group could be significant.Comment: 2 pages of text. Submitted to the Comments section
R. Beck, R. L. Workman
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

New adjusted missing value imputation in multiple regression with simple random sampling and rank set sampling methods.

open access: yesPLoS ONE
This research compared the efficiency of several adjusted missing value imputation methods in multiple regression analysis. The four imputation methods were the following: regression-ratio quartile1,3 (R-RQ1,3) imputation of Al-Omari, Jemain and Ibrahim;
Juthaphorn Sinsomboonthong   +1 more
doaj   +1 more source

Adaptive minimum symbol error rate beamforming assisted receiver for quadrature amplitude modulation systems

open access: yes, 2006
An adaptive beamforming assisted receiver is proposed for multiple antenna aided multiuser systems that employ bandwidth efficient quadrature amplitude modulation (QAM).
Chen, S., Du, H.Q, Hanzo, L.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Smart grid data compression and reconstruction by wavelet packet transform

open access: yesMethodsX
A smart grid is a power network from generation to consumers and provides beneficial, steady, and safe electricity. It utilizes smart meters for billing, phasor measurement units to check the system's health., etc.
Rakhi Jadhav, Anurag Mahajan
doaj   +1 more source

Magnetic Nanoparticle Thermometer: An Investigation of Minimum Error Transmission Path and AC Bias Error

open access: yesSensors, 2015
The signal transmission module of a magnetic nanoparticle thermometer (MNPT) was established in this study to analyze the error sources introduced during the signal flow in the hardware system. The underlying error sources that significantly affected the
Zhongzhou Du   +3 more
doaj   +1 more source

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