Results 41 to 50 of about 1,088,621 (289)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Parameter N Analysis on the Rational-Talbot Algorithm for Numerical Inversion of Laplace Transform

open access: yesVetor, 2021
This article investigates the numerical inversion of the Laplace Transform by the Rational-Talbot method and analyzes the influence on the variation of the free parameter N established by the technique when applied to certain functions.
Elisandra Freitas   +4 more
doaj   +3 more sources

Realization of Analog Wavelet Filter Using Hybrid Genetic Algorithm for On-Line Epileptic Event Detection

open access: yesIEEE Access, 2020
As the evolution of traditional electroencephalogram (EEG) monitoring unit for epilepsy diagnosis, wearable ambulatory EEG (WAEEG) system transmits EEG data wirelessly, and can be made miniaturized, discrete and social acceptable.
Wenshan Zhao   +4 more
doaj   +1 more source

Pointwise simultaneous approximation by rational operators [PDF]

open access: yes, 1991
We obtain pointwise simultaneous approximation estimates for rational operators which are not possible by algebraic ...
Mastroianni, G   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Approximation by Rational Functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1986
Making use of the Hardy-Littlewood maximal function, we give a new proof of the following theorem of Pekarski: If f ′ f’
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Operational characteristic and approximation performance analysis of Oustaloup fractance circuits

open access: yes四川大学学报. 自然科学版, 2016
In this paper, we investigated operational characteristics and approximation performance of Oustaloup fractance rational approximation from a new perspective of fractional calculus operation.
LIU Pan-Pan, YUAN Xiao, TAO Lei, YI Zhou
doaj  

Multivariate Rational Approximation

open access: yesCoRR, 2019
We present two approaches for computing rational approximations to multivariate functions, motivated by their effectiveness as surrogate models for high-energy physics (HEP) applications. Our first approach builds on the Stieltjes process to efficiently and robustly compute the coefficients of the rational approximation. Our second approach is based on
Anthony P. Austin   +5 more
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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