Results 51 to 60 of about 19,646 (265)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A Covariance-Free Strictly Complex-Valued Relevance Vector Machine for Reducing the Order of Linear Time-Invariant Systems

Mathematics
Multiple-input multiple-output (MIMO) linear time-invariant (LTI) systems exhibit enormous computational costs for high-dimensional problems. To address this problem, we propose a novel approach for reducing the dimensionality of MIMO systems. The method
Weixiang Xie, Jie Song
doaj   +1 more source

Rational Approximation

Notices of the American Mathematical Society
Rational approximation has gone through a transformation in recent years with the appearance of algorithms that make computing rational approximations easy. The aim of this short story is not to describe these algorithms, but to show how beautifully they can reveal the power of rational functions and the mathematics of rational approximation.
openaire   +2 more sources

Approximation by Rational Functions [PDF]

Proceedings of the American Mathematical Society, 1986
Making use of the Hardy-Littlewood maximal function, we give a new proof of the following theorem of Pekarski: If f ′ f’
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

MPQA method applied to the plasma dispersion function

AIP Advances
A new approximation method for the plasma dispersion function Z(ζ) is presented. Multipoint quasi-rational approximation technique is used to find a bridge function that connects the power series and the asymptotic expansion of the function Z(ζ) using ...
E. Morales-Campaña, P. Martin
doaj   +1 more source

Simultaneous Diophantine approximation of rationals by rationals

Journal of Number Theory, 1986
For positive integers \(n\geq 2\), \(B\geq 2\), let \(S_ n(B)\) denote the set of rational vectors \(\alpha =(a_ 1/B,...,a_ n/B)\) with \(a_ j\in {\mathbb{Z}}\), \(0\leq a_ j0\), define N(\(\alpha\),\(\Delta)\) as the number of vectors \(\zeta =(x_ 1/x,...,x_ n/x)\) with \(1\leq ...
Lagarias, Jeffrey C, Hastad, Johan T
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Rational approximation of 𝐱ⁿ

Proceedings of the American Mathematical Society, 2018
Let E k k (
Nakatsukasa, Y, Trefethen, L
openaire   +2 more sources