Results 61 to 70 of about 19,451 (267)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Approximation by rational functions in Morrey-Smirnov classes

Kuwait Journal of Science, 2018
In this article, we investigate the direct problem of approximation theory in Morrey-Smirnov classes of analytic functions, defined on a doubly-connected domain bounded by two sufficiently smooth curves.
Mohammad Ali, Suliman Mahmoud, Ahmed kinj   +2 more
doaj  

Fejer means of rational Fourier – Chebyshev series and approximation of function |x|s

Журнал Белорусского государственного университета: Математика, информатика, 2019
Approximation properties of Fejer means of Fourier series by Chebyshev – Markov system of algebraic fractions and approximation by Fejer means of function |x|s, 0 < s < 2, on the interval [−1,1], are studied.
Pavel G. Patseika, Yauheni A. Rouba
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

A Covariance-Free Strictly Complex-Valued Relevance Vector Machine for Reducing the Order of Linear Time-Invariant Systems

Mathematics
Multiple-input multiple-output (MIMO) linear time-invariant (LTI) systems exhibit enormous computational costs for high-dimensional problems. To address this problem, we propose a novel approach for reducing the dimensionality of MIMO systems. The method
Weixiang Xie, Jie Song
doaj   +1 more source

Neural-Network-Based Curve Fitting Using Totally Positive Rational Bases

Mathematics, 2020
This paper proposes a method for learning the process of curve fitting through a general class of totally positive rational bases. The approximation is achieved by finding suitable weights and control points to fit the given set of data points using a ...
Rocio Gonzalez-Diaz, E. Mainar, Eduardo Paluzo-Hidalgo, B. Rubio   +3 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

On monotone rational approximation

Journal of Approximation Theory, 2005
The author solves a problem raised by R. A. DeVore in his several lectures during the last 15 years. The author finds the exact order of monotone rational approximation for the Sobolev classes \(W_p^1\). He proves that if \(f\) is an absolutely continuous function on \([0, 1]\) satisfying \(f'\in L_p[0,1 ...
openaire   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source