Results 61 to 70 of about 1,088,621 (289)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A Covariance-Free Strictly Complex-Valued Relevance Vector Machine for Reducing the Order of Linear Time-Invariant Systems

Mathematics
Multiple-input multiple-output (MIMO) linear time-invariant (LTI) systems exhibit enormous computational costs for high-dimensional problems. To address this problem, we propose a novel approach for reducing the dimensionality of MIMO systems. The method
Weixiang Xie, Jie Song
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

MPQA method applied to the plasma dispersion function

AIP Advances
A new approximation method for the plasma dispersion function Z(ζ) is presented. Multipoint quasi-rational approximation technique is used to find a bridge function that connects the power series and the asymptotic expansion of the function Z(ζ) using ...
E. Morales-Campaña, P. Martin
doaj   +1 more source

Simultaneous Diophantine approximation of rationals by rationals

Journal of Number Theory, 1986
For positive integers \(n\geq 2\), \(B\geq 2\), let \(S_ n(B)\) denote the set of rational vectors \(\alpha =(a_ 1/B,...,a_ n/B)\) with \(a_ j\in {\mathbb{Z}}\), \(0\leq a_ j0\), define N(\(\alpha\),\(\Delta)\) as the number of vectors \(\zeta =(x_ 1/x,...,x_ n/x)\) with \(1\leq ...
Lagarias, Jeffrey C, Hastad, Johan T
openaire   +1 more source

Compressed Passive Macromodeling [PDF]

, 2012
This paper presents an approach for the extraction of passive macromodels of large-scale interconnects from their frequency-domain scattering responses. Here, large scale is intended both in terms of number of electrical ports and required dynamic model ...
Olivadese, Salvatore Bernardo, Grivet-Talocia, S., GRIVET TALOCIA, STEFANO   +2 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Rational approximation of 𝐱ⁿ

Proceedings of the American Mathematical Society, 2018
Let E k k (
Nakatsukasa, Y, Trefethen, L
openaire   +2 more sources

Bivariate n-term rational approximation [PDF]

, 2005
We study nonlinear approximation in Lp(R2 ...
Park, Kyungwon
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source