Results 41 to 50 of about 596,831 (304)

Rational expectations modelling in O.R [PDF]

open access: yes, 1984
The conventional OR approach to managing a system is, in outline, firstly to create a model of the existing system, secondly, to investigate changes in the model which improve or control the behaviour of the model and thirdly, to implement these changes ...
Phelps, R I, Warwick, J P
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Rational Expectations, the Lucas Critique and the Optimal Control of Macroeconomic Models: A Historical Analysis of Basic Developments in the 20th Century [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2011
In this paper, we first consider the role of rational expectations, the Lucas critique and the policy ineffectiveness debate in economic applications of optimal control theory. The problem of time-inconsistency in optimal control of macro-economic models
Masoud Derakhshan
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

L’analyse économique est-elle intemporelle ?

open access: yesTemporalités, 2004
To answer this question, we develop three issues: first, the assessment of the future is the core issue in studying expectations; second, dynamic economic modeling often leads to represent Time as a series of economic equilibriums; lastly, the « New ...
Antoine Parent
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

RATIONAL EXPECTATIONS MODEL AND POSSIBILITIES TO USE IT IN MANAGEMENT OF MODERN AIRPORTS

open access: yesRussian Journal of Economics and Law, 2013
Objective: description of the rational expectations model and analysis of possibilities to use it in strategic management of airport complexes. Method: abstract-logical. Results: Development of an airport (airport complex) is in its progressing along the
O. N. Gorbachova
doaj  

Equilíbrio e ciclos Equilibrium and cycles

open access: yesRevista de Economia Contemporânea, 2005
A agenda de pesquisa relacionada a modelos de ciclos reais de negócios (Real-Business-Cycle models - RBC) apresentou um crescimento exponencial desde seu surgimento, no início da década de 1980.
Matheus Albergaria de Magalhães
doaj   +1 more source

Anticipated Fiscal Policy and Adaptive Learning [PDF]

open access: yes, 2007
We consider the impact of anticipated policy changes when agents form expectations using adaptive learning rather than rational expectations. To model this we assume that agents combine limited structural knowledge with a standard adaptive learning rule.
Evans, George W.   +2 more
core   +2 more sources

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